找到约 39 条 “Rac1-IN-3” 相关结果 （用时 0.104 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
| M41932 | Rac1-IN-3 | Rac1-IN-3 | Ras |
| Rac1-IN-3 是一种 Rac1 抑制剂，其 IC50 为 46.1 μM。 | |||
| M47474 | ChemBridge-18192983 | ChemBridge化合物-18192983 | Screening Compounds and Building Blocks |
| N-[rac-(1R,2R)-2-(dimethylamino)cyclopentyl]-4-oxo-3,4-dihydrophthalazine-1-carboxamide (18192983) | |||
| ChemBridge特有类药化合物/先导化合物-18192983，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M47538 | ChemBridge-20677158 | ChemBridge化合物-20677158 | Screening Compounds and Building Blocks |
| rac-(3S,4S)-4-(dimethylamino)-1-(isoquinolin-5-ylmethyl)pyrrolidin-3-ol (20677158) | |||
| ChemBridge特有类药化合物/先导化合物-20677158，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M47639 | ChemBridge-24622876 | ChemBridge化合物-24622876 | Screening Compounds and Building Blocks |
| 6-{[rac-(3aR,6S,7aS)-3a,6-dimethoxyoctahydro-1H-indol-1-yl]methyl}-1-methyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (24622876) | |||
| ChemBridge特有类药化合物/先导化合物-24622876，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M47849 | ChemBridge-33097236 | ChemBridge化合物-33097236 | Screening Compounds and Building Blocks |
| N-[rac-(3R,4R)-3-hydroxy-1-(1,3-thiazol-4-ylmethyl)piperidin-4-yl]-3-isopropoxybenzamide (33097236) | |||
| ChemBridge特有类药化合物/先导化合物-33097236，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M47882 | ChemBridge-34357148 | ChemBridge化合物-34357148 | Screening Compounds and Building Blocks |
| rac-(4aS,6aS,10aS,10bS)-5-[(4-isopropyl-4H-1,2,4-triazol-3-yl)methyl]decahydro-1H,10aH-dipyrano[4,3-b:4',3'-d]pyridin-10a-ol (34357148) | |||
| ChemBridge特有类药化合物/先导化合物-34357148，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M47891 | ChemBridge-34649347 | ChemBridge化合物-34649347 | Screening Compounds and Building Blocks |
| 2-amino-N-[rac-(1S,5R,6S)-2-oxabicyclo[3.2.0]hept-6-yl]-4-phenylpyrimidine-5-carboxamide (34649347) | |||
| ChemBridge特有类药化合物/先导化合物-34649347，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M47892 | ChemBridge-34660662 | ChemBridge化合物-34660662 | Screening Compounds and Building Blocks |
| 5-{[rac-(4aS,8aS)-4a-(3,6-dihydro-2H-pyran-4-yl)hexahydro-2H-pyrano[4,3-b]pyridin-1(5H)-yl]carbonyl}pyrazin-2-ol (34660662) | |||
| ChemBridge特有类药化合物/先导化合物-34660662，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M47940 | ChemBridge-36734388 | ChemBridge化合物-36734388 | Screening Compounds and Building Blocks |
| 6-[rac-(1R,5S)-3-azabicyclo[3.2.1]oct-3-yl]-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (36734388) | |||
| ChemBridge特有类药化合物/先导化合物-36734388，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M48012 | ChemBridge-39807066 | ChemBridge化合物-39807066 | Screening Compounds and Building Blocks |
| rac-(1S,3S,7aR)-N-[3-(1H-imidazol-2-yl)propyl]-3-phenylhexahydro-1H-pyrrolizine-1-carboxamide (39807066) | |||
| ChemBridge特有类药化合物/先导化合物-39807066，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M48575 | ChemBridge-62946057 | ChemBridge化合物-62946057 | Screening Compounds and Building Blocks |
| rac-(1S,3S,7aR)-N-[2-(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)ethyl]-3-phenylhexahydro-1H-pyrrolizine-1-carboxamide (62946057) | |||
| ChemBridge特有类药化合物/先导化合物-62946057，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M48597 | ChemBridge-63871161 | ChemBridge化合物-63871161 | Screening Compounds and Building Blocks |
| rac-(3R,4R)-1-[(3-chloro-1-benzothien-2-yl)methyl]-4-fluoropyrrolidin-3-ol (63871161) | |||
| ChemBridge特有类药化合物/先导化合物-63871161，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M48650 | ChemBridge-66249060 | ChemBridge化合物-66249060 | Screening Compounds and Building Blocks |
| N-[rac-(1R,2R,4S)-bicyclo[2.2.1]hept-2-yl]-7-methyl[1,2,4]triazolo[4,3-a]pyrimidine-3-carboxamide (66249060) | |||
| ChemBridge特有类药化合物/先导化合物-66249060，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M48652 | ChemBridge-66255797 | ChemBridge化合物-66255797 | Screening Compounds and Building Blocks |
| rac-(3S,4S)-1-(cyclohex-1-en-1-ylmethyl)-4-(dimethylamino)piperidin-3-ol (66255797) | |||
| ChemBridge特有类药化合物/先导化合物-66255797，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M48719 | ChemBridge-69714971 | ChemBridge化合物-69714971 | Screening Compounds and Building Blocks |
| rac-(1S,3S,7aR)-N-{2-[(methylsulfonyl)amino]ethyl}-3-phenylhexahydro-1H-pyrrolizine-1-carboxamide (69714971) | |||
| ChemBridge特有类药化合物/先导化合物-69714971，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M48724 | ChemBridge-70008783 | ChemBridge化合物-70008783 | Screening Compounds and Building Blocks |
| rac-(3S,4S)-1-(2,3-dihydro-1H-inden-2-yl)-4-(dimethylamino)pyrrolidin-3-ol (70008783) | |||
| ChemBridge特有类药化合物/先导化合物-70008783，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M48739 | ChemBridge-70530177 | ChemBridge化合物-70530177 | Screening Compounds and Building Blocks |
| N,N-dimethyl-1-[rac-(1R,5S,6r)-3-(4,7,8-trimethylquinolin-2-yl)-3-azabicyclo[3.1.0]hex-6-yl]methanamine (70530177) | |||
| ChemBridge特有类药化合物/先导化合物-70530177，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M48793 | ChemBridge-73097882 | ChemBridge化合物-73097882 | Screening Compounds and Building Blocks |
| rac-(1S,3S,7aR)-N-(3,4-difluorobenzyl)-3-phenylhexahydro-1H-pyrrolizine-1-carboxamide (73097882) | |||
| ChemBridge特有类药化合物/先导化合物-73097882，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M48852 | ChemBridge-75827136 | ChemBridge化合物-75827136 | Screening Compounds and Building Blocks |
| rac-(3S,4S)-1-(cyclohex-1-en-1-ylmethyl)-4-[(dimethylamino)methyl]piperidin-3-ol (75827136) | |||
| ChemBridge特有类药化合物/先导化合物-75827136，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M48876 | ChemBridge-77340801 | ChemBridge化合物-77340801 | Screening Compounds and Building Blocks |
| rac-(1S,3aR,6aS)-2-acetyl-5-(6-methyl-2-pyridinyl)-1-phenyloctahydropyrrolo[3,4-c]pyrrole (77340801) | |||
| ChemBridge特有类药化合物/先导化合物-77340801，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M48908 | ChemBridge-78992340 | ChemBridge化合物-78992340 | Screening Compounds and Building Blocks |
| 9-hydroxy-2-{[rac-(3aR,6S,7aS)-6-hydroxy-3a-methoxyoctahydro-1H-indol-1-yl]methyl}-4H-pyrido[1,2-a]pyrimidin-4-one (78992340) | |||
| ChemBridge特有类药化合物/先导化合物-78992340，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M48962 | ChemBridge-81167319 | ChemBridge化合物-81167319 | Screening Compounds and Building Blocks |
| rac-(1S,3S,7aR)-N-({3-[(methylthio)methyl]-1,2,4-oxadiazol-5-yl}methyl)-3-phenylhexahydro-1H-pyrrolizine-1-carboxamide (81167319) | |||
| ChemBridge特有类药化合物/先导化合物-81167319，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M49004 | ChemBridge-83629902 | ChemBridge化合物-83629902 | Screening Compounds and Building Blocks |
| 2-({rac-(3aR,6S,7aS)-3a-methoxy-1-[3-(4H-1,2,4-triazol-4-yl)propanoyl]octahydro-1H-indol-6-yl}oxy)ethanol (83629902) | |||
| ChemBridge特有类药化合物/先导化合物-83629902，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M49076 | ChemBridge-86690398 | ChemBridge化合物-86690398 | Screening Compounds and Building Blocks |
| rac-(3R,4R)-1-[(3,5-dimethyl-1-benzofuran-2-yl)methyl]-4-fluoropyrrolidin-3-ol (86690398) | |||
| ChemBridge特有类药化合物/先导化合物-86690398，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M49095 | ChemBridge-87773572 | ChemBridge化合物-87773572 | Screening Compounds and Building Blocks |
| rac-(1S,3S,7aR)-3-phenyl-N-(1H-1,2,4-triazol-3-ylmethyl)hexahydro-1H-pyrrolizine-1-carboxamide (87773572) | |||
| ChemBridge特有类药化合物/先导化合物-87773572，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M49114 | ChemBridge-88815309 | ChemBridge化合物-88815309 | Screening Compounds and Building Blocks |
| N-[rac-(3R,4R)-3-hydroxy-1-(1,3-thiazol-4-ylmethyl)piperidin-4-yl]quinoxaline-6-carboxamide (88815309) | |||
| ChemBridge特有类药化合物/先导化合物-88815309，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M49169 | ChemBridge-91440220 | ChemBridge化合物-91440220 | Screening Compounds and Building Blocks |
| rac-(4aR,8aS)-6-(2-fluoro-5-methoxybenzyl)-8a-phenylhexahydro-1H-pyrido[3,4-b][1,4]oxazin-2(3H)-one (91440220) | |||
| ChemBridge特有类药化合物/先导化合物-91440220，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M50078 | ChemBridge-46238927 | ChemBridge化合物-46238927 | Screening Compounds and Building Blocks |
| 4-(3-aminopropoxy)-N-[rac-(3S,4S)-4-methoxy-1-methylpyrrolidin-3-yl]benzamide (46238927) | |||
| ChemBridge特有类药化合物/先导化合物-46238927，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M50138 | ChemBridge-36597957 | ChemBridge化合物-36597957 | Screening Compounds and Building Blocks |
| rac-(1R,3S)-3-({[2-(1,3-thiazol-2-yl)ethyl]amino}carbonyl)cyclopentanecarboxylic acid (36597957) | |||
| ChemBridge特有类药化合物/先导化合物-36597957，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
M55282
|
ChemBridge-56678443 | ChemBridge化合物-56678443 | Screening Compounds and Building Blocks |
| rac-(3S,4S)-4-piperidin-1-yl-1-quinolin-4-ylpyrrolidin-3-ol | |||
| ChemBridge特有类药化合物/先导化合物-56678443，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M11542
|
Ochromycinone | 抑胃酶氨酰-21 | STAT |
| (Rac)-STA-21；STA 21 | |||
| Ochromycinone ((Rac)-STA-21)是一种天然抗生素，也是一个选择性的STAT3抑制剂。Ochromycinone 可抑制 STAT3 DNA结合活性，STAT3 二聚化。Ochromycinone 具有抗癌和抗菌活性。 | |||
| M20527 | Deracoxib | Deracoxib | COX |
| SC-046 | |||
| Deracoxib is a COX-2 inhibitor with >48-fold selectivity over COX-1. It also exhibits inhibitory activity against phosphodiesterase (Ki = 3.6 μM against human PDE4D3). | |||
| M20694 | Bay 41-4109 racemate | Bay 41-4109 racemate | Anti-infection |
| BAY41-4109 Racemic | |||
| BAY 41-4109 racemate is a mixture of R-isomer of BAY 41-4109 and S-isomer of BAY 41-4109. BAY 41-4109 an antiviral compound that inhibits human hepatitis B virus (HBV) with IC50 of 53 nM. | |||
| M20775 | SEC inhibitor KL-1 | SEC inhibitor KL-1 | Others |
| KL-1 | |||
| SEC inhibitor KL-1 (KL-1) is a potent and selective inhibitor of super elongation complex (SEC) that disrupts the interaction between the SEC scaffolding protein AFF4 and P-TEFb, resulting in impaired release of Pol II from promoter-proximal pause sites and a reduced average rate of processive transcription elongation. KL-1 exhibits an dose-dependent inhibitory effect on AFF4-CCNT1 interaction with Ki of 3.48 μM. | |||
| M20824
|
Sulfopin | Sulfopin | Others |
| PIN1-3 | |||
| Sulfopin 是一种高选择性的Pin1（Peptidyl-prolyl isomerase NIMA-interacting 1）共价抑制剂。Sulfopin在多种肿瘤细胞系中表现出抗增殖活性。此外，Sulfopin（2 μM）处理HEK293细胞可下调Myc的转录。在小鼠神经母细胞瘤、胰腺癌等模型中，Sulfopin可抑制肿瘤细胞的增殖。Sulfopin还能用于肿瘤干细胞的研究，它可降低肿瘤干细胞标志物（OLIG2）的表达，从而抑制肿瘤干细胞的活性。 | |||
| M25536
|
Recombinant Human CXCL13/BCA-1 (E. coli) | 重组人CXCL13/BCA-1蛋白 (E. coli) | Cytokines and Growth Factors |
| CXC chemokine BLC; Small-inducible cytokine B13 | |||
| CXCL13, also known as B-lymphocyte chemoattractant (BLC), is a CXC chemokine that is constitutively expressed in secondary lymphoid organs. Recombinant human CXCL13 is a single non-glycosylated polypeptide chain containing 87 amino acids and mature human BCA-1 shares 64 % amino acid sequence similarity with the murine protein and 23–34 % amino acid sequence identity with other known CXC chemokines. Determined by a chemotaxis bioassay using human B cells, the biological activity is in a concentration range of 1.0-10 ng/ml. | |||
| M29868 | ZINC69391 | ZINC69391 | Ras |
| ZINC69391 是一种特异的 Rac1 抑制剂，通过在 Rac1 表面掩蔽 Trp56 残基来干扰 Rac1-GEF 的相互作用。ZINC69391 干扰 Rac1 与 Dock180 的相互作用，降低 Rac1-GTP水平。ZINC69391 诱导细胞凋亡，具有抗增殖和抗转移作用。 | |||
| M30099 | (rac)-AG-205 | (rac)-AG-205 | NF-κB |
| (rac)-AG-205 是一种有效的孕激素受体膜组分1 (Pgrmc1)抑制剂，可以诱导参与甾醇合成的基因，包括与 PGRMC1 形成复合物的 INSIG1 蛋白。(rac)-AG-205 可以通过阻止 NF-kB 信号和 BDNF/PI3K/AKT 通路的激活来阻止神经元对缺氧缺血的抵抗。 | |||
| M31066 | (Rac)-PF-184 hydrate | (Rac)-PF-184 hydrate | IκB/IKK |
| (Rac)-PF-184 hydrate 是一种有效的 inhibitory factor-κB kinase 2 (IKK-2) 抑制剂，IC50 值为 37 nM。(Rac)-PF-184 hydrate 具有抗炎作用。 | |||
