找到约 9 条 “OT-R antagonist 1” 相关结果 （用时 0.141 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
| M29995 | OT-R antagonist 1 | OT-R antagonist 1 | Oxytocin Receptor |
| Oxytocin receptor antagonist 1 | |||
| OT-R antagonist 1是一种新型有效的选择性非肽类OT-R拮抗剂, 抑制催产素诱发的细胞内Ca2+活动（IC50=8nM）。 | |||
| M8700 | PCS1055 dihydrochloride | PCS1055 dihydrochloride | Others |
| PCS1055 is a potent and selective muscarinic M4 acetylcholine receptor competitive antagonist that exhibits >100-fold selectivity over M1-, M3-, and M5-receptors and 30-fold selectivity at the M2 receptor. | |||
| M8856 | WAY-100135 dihydrochloride | WAY-100135 dihydrochloride | 5-HT Receptor |
| WAY-100135 dihydrochloride is a potent, selective 5-HT1A receptor antagonist (IC50 = 15 nM). | |||
| M20515 | Emedastine | Emedastine | Histamine Receptor |
| Emedastine is a potent, high affinity histamine H1-receptor-selective antagonist with Ki of 1.3 ±0.1 nM for H1-receptors while considerably weaker at H2- (K1 = 49,067 ± 11,113 nM) and H3-receptors (Ki = 12,430 ± 1,282 nM). | |||
| M20620 | ONO-7300243 | ONO-7300243 | Others |
| ONO 7300243, ONO7300243 | |||
| ONO-7300243 is a novel, potent LPA1(Lysophosphatidic Acid Receptor) antagonist with an IC50 of 160 nM. | |||
| M20627 | A2AR antagonist 1 | A2AR antagonist 1 | Adenosine Receptor |
| A2AR antagonist 1 is a potent A2AR (Adenosine A2A Receptor) antagonist with Ki values of 4 nM and 264 nM for A2AR and A1R, respectively. | |||
| M20977 | BAY 2416964 | BAY 2416964 | Aryl hydrocarbon Receptor |
| BAY 2416964 (compound 192) is a potent and orally active antagonist of aryl hydrocarbon receptor (AhR) with IC50 of 341 nM. BAY 2416964 has the potential in the treatment of solid tumors. | |||
| M27999 | TASP0376377 | TASP0376377 | Prostaglandin Receptor |
| TASP0376377 is a potent and selective CRTH2 antagonist (IC50: 13 nM). TASP0376377 has binding affinity for CRTH2 (IC50: 19 nM). | |||
M58144
|
Recombinant Human IL-1R1 (HEK293, C-6His) | 重组人IL-1R1 蛋白 (HEK293, C-6His) | Cytokines and Growth Factors |
| Interleukin-1 Receptor Type 1; IL-1R-1 | |||
| Interleukin 1 receptor, type I (IL-1R1) is an interleukin receptor that belongs to the interleukin-1 receptor family. IL-1R1 is an important mediator involved in many cytokine induced immune and inflammatory responses. It binds to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Recombinant IL1 receptor Type I is a potent antagonist of IL1 action. | |||
