OAC-2 - 搜索结果

找到约 49 条 “OAC-2” 相关结果（用时 0.175 秒）

目录号	产品名称	中文名称	靶点
M4923	Cyanoacetohydrazide	氰乙酰肼；氰基乙酰肼；抗痨肼	Antibiotic
	Cyanoacetic hydrazide; 2-Cyanoacetohydrazide
	Cyanoacetohydrazide is an anti-TB drug.
M7074	OAC-2	OAC-2	mTOR
M7074	OAC-2是一种Oct4激剂，能通过Oct4基因启动子激活表达，并可提高 iPSC 重编程效率。
M13317	ChemBridge-81439629	ChemBridge化合物-81439629	Screening Compounds and Building Blocks
	1-[3-(2-methyl-1-piperidinyl)propyl]-1H-benzimidazole bis(trifluoroacetate) (81439629)
	ChemBridge特有类药化合物/先导化合物-81439629，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。
M30931	IA-Alkyne	IA-Alkyne	TRP Channel
	Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide
	IA-Alkyne (Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide) 是一种 TRP 通道 (TRPC) 的激动剂，有潜力用于呼吸道感染相关疾病的研究。IA-Alkyne 可以用来开发同位素标记的探针，用于定量的半胱氨酸反应分析 (cysteine-reactivity)。
M46680	ChemBridge-8896721	ChemBridge化合物-8896721	Screening Compounds and Building Blocks
	2-(6-fluoro-1H-indol-3-yl)-N-(5-methylisoxazol-3-yl)-2-oxoacetamide (8896721)
	ChemBridge特有类药化合物/先导化合物-8896721，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。
M47523	ChemBridge-20189851	ChemBridge化合物-20189851	Screening Compounds and Building Blocks
	rel-(2R,3R)-3-{methyl[3-(3-methylphenoxy)propyl]amino}-2,3-dihydrospiro[indene-1,4'-piperidin]-2-ol bis(trifluoroacetate) (salt) (20189851)
	ChemBridge特有类药化合物/先导化合物-20189851，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。
M47533	ChemBridge-20459631	ChemBridge化合物-20459631	Screening Compounds and Building Blocks
	({1-[1-(4'-methyl-4-biphenylyl)-4-piperidinyl]-3-pyrrolidinyl}methyl)amine bis(trifluoroacetate) (20459631)
	ChemBridge特有类药化合物/先导化合物-20459631，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。
M47641	ChemBridge-24704002	ChemBridge化合物-24704002	Screening Compounds and Building Blocks
	N-[4-(1-phenyl-1H-pyrazol-4-yl)-2-pyrimidinyl]-1,5-pentanediamine trifluoroacetate (24704002)
	ChemBridge特有类药化合物/先导化合物-24704002，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。
M47738	ChemBridge-28570051	ChemBridge化合物-28570051	Screening Compounds and Building Blocks
	1-{[1-(4-fluorophenyl)cyclopropyl]methyl}-3-piperidinol trifluoroacetate (salt) (28570051)
	ChemBridge特有类药化合物/先导化合物-28570051，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。
M47766	ChemBridge-29556462	ChemBridge化合物-29556462	Screening Compounds and Building Blocks
	2-{1-[4-(1,3-dimethyl-1H-pyrazol-4-yl)-2-pyrimidinyl]-4-piperidinyl}-5-fluoro-1H-benzimidazole bis(trifluoroacetate) (29556462)
	ChemBridge特有类药化合物/先导化合物-29556462，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。
M48443	ChemBridge-57320039	ChemBridge化合物-57320039	Screening Compounds and Building Blocks
	(3S)-1-[(4'-fluoro-2-biphenylyl)methyl]-3-pyrrolidinol trifluoroacetate (salt) (57320039)
	ChemBridge特有类药化合物/先导化合物-57320039，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。
M48560	ChemBridge-62317277	ChemBridge化合物-62317277	Screening Compounds and Building Blocks
	N-[4-(1,3-dimethyl-1H-pyrazol-4-yl)-2-pyrimidinyl]-N'-methyl-1,2-ethanediamine trifluoroacetate (62317277)
	ChemBridge特有类药化合物/先导化合物-62317277，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。
M48612	ChemBridge-64339692	ChemBridge化合物-64339692	Screening Compounds and Building Blocks
	3-(1,3-benzodioxol-5-yl)-5-[rel-(1S,4S)-bicyclo[2.2.1]hept-5-en-2-ylmethyl]-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine trifluoroacetate (64339692)
	ChemBridge特有类药化合物/先导化合物-64339692，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。
M48788	ChemBridge-72839956	ChemBridge化合物-72839956	Screening Compounds and Building Blocks
	2-[[2-(2-chloro-4-fluorophenyl)ethyl](isopropyl)amino]ethanol trifluoroacetate (salt) (72839956)
	ChemBridge特有类药化合物/先导化合物-72839956，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。
M48936	ChemBridge-80121052	ChemBridge化合物-80121052	Screening Compounds and Building Blocks
	5-fluoro-2-{1-[4-(1,3,5-trimethyl-1H-pyrazol-4-yl)-2-pyrimidinyl]-4-piperidinyl}-1H-benzimidazole bis(trifluoroacetate) (80121052)
	ChemBridge特有类药化合物/先导化合物-80121052，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。
M48947	ChemBridge-80692514	ChemBridge化合物-80692514	Screening Compounds and Building Blocks
	rel-(2R,3R)-3-[(3-methoxypropyl)(methyl)amino]-2,3-dihydrospiro[indene-1,4'-piperidin]-2-ol bis(trifluoroacetate) (salt) (80692514)
	ChemBridge特有类药化合物/先导化合物-80692514，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。
M49281	ChemBridge-96221706	ChemBridge化合物-96221706	Screening Compounds and Building Blocks
	5-{[4-(phenoxyacetyl)-1-piperazinyl]carbonyl}-1,3-benzothiazol-2-amine trifluoroacetate (96221706)
	ChemBridge特有类药化合物/先导化合物-96221706，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。
M49366	Boc-Glycine	BOC-甘氨酸	Others
	N-tert-Butoxycarbonyl-2-aminoacetic acid; NSC 127669
	Boc-Glycine是一种甘氨酸衍生物，可用于多肽的合成。
M50051	ChemBridge-24387693	ChemBridge化合物-24387693	Screening Compounds and Building Blocks
	6-(2-aminoethyl)-2-[4-({methyl[(3-methyl-2-pyridinyl)methyl]amino}methyl)phenyl]-4(3H)-pyrimidinone bis(trifluoroacetate) (24387693)
	ChemBridge特有类药化合物/先导化合物-24387693，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。
M50091	ChemBridge-28084000	ChemBridge化合物-28084000	Screening Compounds and Building Blocks
	6-(2-aminoethyl)-2-[4-({methyl[(2E)-3-phenyl-2-propen-1-yl]amino}methyl)phenyl]-4(3H)-pyrimidinone bis(trifluoroacetate) (28084000)
	ChemBridge特有类药化合物/先导化合物-28084000，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。
M51223	Trifluoroacetyl tripeptide-2	Trifluoroacetyl tripeptide-2	Others
M51223	Trifluoroacetyl tripeptide-2 是一种具有抗衰老 (anti-aging) 作用的生物活性肽，已被报道用作化妆品成分。
M51341	H-D-MeAla-EtVaI-VaI-MeLeu-AIa-D-AIa-MeLeu-MeLeu-MeVaI-MeBmt(OAc)-Abu-O-CH2-CH2-NHMe	H-D-MeAla-EtVaI-VaI-MeLeu-AIa-D-AIa-MeLeu-MeLeu-MeVaI-MeBmt(OAc)-Abu-O-CH2-CH2-NHMe	Others
M51341	H-D-MeAla-EtVal-Val-MeLeu-AIa-D-AIa-MeLeu-MeLeu-MeVal-MeBmt(OAc)-Abu-O-CH2-CH2-NHMe 是一种非免疫抑制性环孢菌素 A 衍生物。
M57549	2-[(Azidoacety)amino]-2-deoxy-D-mannose	2-[(Azidoacety)amino]-2-deoxy-D-mannose	Others
M57549	2-[(Azidoacety)amino]-2-deoxy-D-mannose
M2896	OAC1	OAC1	Others
M2896	OAC1 (Oct4-activating compound 1)是一种有效的 Oct4 激活剂，能激活 Oct4 和 Nanog 启动子，促进诱导多功能干细胞 (iPSC) 的形成，以及通过上调 HOXB4 表达激活 OCT4。此外，OAC1 还能增加Oct4-Nanog-Sox2 三联体和 TET1 的转录，并可通过提高效率和缩短重编程时间，促进细胞的重编程。
M3631	AZ505 ditrifluoroacetate	AZ505 ditrifluoroacetate	Histone Methyltransferase
	AZ 505 ditrifluoroacetate; AZ-505 ditrifluoroacetate
	AZ505 ditrifluoroacetate 是一种强效、高选择性的致癌蛋白SMYD2抑制剂(IC50=0.12 uM)，具有潜在的抗癌活性。
M6505	BIBO 3304 trifluoroacetate	BIBO 3304 trifluoroacetate	Neuropeptide Receptor
M6505	BIBO 3304 trifluoroacetate（BIBO 3304三氟乙酸酯）是一种精氨酸酰胺衍生物，同时也是选择性的，高亲和力的NPY Y1受体拮抗剂，作用于人类和大鼠的Y1受体上时，IC50值分别为0.38±0.06 nM和0.72±0.42 nM，具有抗焦虑活性。
M7207	Ro 26-4550 trifluoroacetate	Ro 26-4550 trifluoroacetate	Others
M7207	Ro 26-4550 trifluoroacetate is a competitive inhibitor of IL-2/ IL-2Rα receptor interaction.
M8278	MLS000389544	MLS000389544	Others
M8278	MLS000389544 is a selective and potent methylsulfonylnitrobenzoate thyroid hormone receptor β (TRβ) antagonist that blocks the association of TRβ with steroid receptor coactivator 2 (SRC2).
M8470	SB290157 trifluoroacetate salt	SB290157 trifluoroacetate salt	Complement System
	SB290157 TFA
	SB290157 trifluoroacetate是一种选择性的C3a受体的拮抗剂，IC50值为200 nM。
M9094	EG00229 Trifluoroacetate salt	EG00229 Trifluoroacetate salt	VEGFR/PDGFR
	EG-00229 Trifluoroacetate
	EG00229 Trifluoroacetate能抑制neuropilin-1与VEGFA的相互作用，能抑制125I-VEGF与PAE/NRP1细胞的结合，IC50为8 uM。
M10728	Cyclo(RGDyK) trifluoroacetate	Cyclo(RGDyK) trifluoroacetate	Integrin
M10728	Cyclo(RGDyK) trifluoroacetate 是一种有效的选择性 αVβ3 整联蛋白 (integrin) 抑制剂，IC50 为 20 nM。
M11031	2-Chloroacetamide	氯乙酰胺	Antibiotic
M11031	2-Chloroacetamide 是一种防腐剂，是旱地和水田的除草剂。2-Chloroacetamide 是农业，胶水，油漆和涂料中的杀菌剂。 2-Chloroacetamide 可抑制超长链脂肪酸延伸酶。
M11039	Pyrazoloacridine	Pyrazoloacridine	Topoisomerase
	NSC 366140
	Pyrazoloacridine (NSC 366140) 具有抗癌活性，抑制拓扑异构酶 1 和 2 的活性 (topoisomerases 1 and 2)。Pyrazoloacridine (NSC 366140) 对 K562 髓系白血病细胞中的 IC50 值为 1.25 μM (24 h)。
M11146	Oxaloacetic acid	草酰乙酸	Metabolite/Endogenous Metabolite
	2-Oxosuccinic acid
	Oxaloacetic acid (2-Oxosuccinic acid) 是一种代谢中间体，涉及多种途径，如柠檬酸循环、葡萄糖异生、尿素循环、乙醛酸循环、氨基酸合成和脂肪酸合成。
M13938	ALX 40-4C Trifluoroacetate	ALX 40-4C Trifluoroacetate	CXCR
M13938	ALX 40-4C Trifluoroacetate 是一种趋化因子受体 (CXCR4) 抑制剂，能够抑制 SDF-1 与 CXCR4 结合，Ki 值为 1 μM，具有抗 HIV-1 作用；ALX 40-4C Trifluoroacetate 同时为 APJ 受体拮抗剂，IC50 值为 2.9 μM。
M14064	Pasireotide ditrifluoroacetate	帕瑞肽二三氟乙酸盐	Others
	SOM230 ditrifluoroacetate; Pasireotide TFA salt
	Pasireotide (SOM230) ditrifluoroacetate 是一种长效的环己肽生长激素抑制素类似物，同时也是大环类化合物，可以提高生长抑素受体(SSTR)的激动剂活性，对 sst1/2/3/4/5 的 pKi 分别为 8.2/9.0/9.1/<7.0/9.9。Pasireotide ditrifluoroacetate 具有抗分泌、抗增殖和促凋亡活性。
M14208	Endovion	Endovion	Chloride Channel
	NS3728
	Endovion (NS3728) 是一种阴离子通道抑制剂 (如氯离子通道)，也是特异性的 VRAC/VSOAC 阻断剂。Endovion (NS3728) 还是一种 ANO1 抑制剂。
M14503	GSK256066 Trifluoroacetate	GSK256066 Trifluoroacetate	PDE
M14503	GSK256066 Trifluoroacetate 是一种选择性、高亲和力的 PDE 抑制剂，抑制 PDE4B 的 IC50 值为 3.2 pM。GSK256066 Trifluoroacetate 被开发用于慢性阻塞性肺病的研究。
M14522	Pepstatin Trifluoroacetate	抑肽素三氟醋酸盐	Proteasome
	Pepstatin A Trifluoroacetate
	Pepstatin Trifluoroacetate (Pepstatin A Trifluoroacetate) 是由放线菌类产生的一种特异性的天冬氨酸蛋白酶 (aspartic proteases) 抑制剂，能够抑制 hemoglobin-pepsin，hemoglobin-proctase，casein-pepsin，casein-proctase，casein-acid protease 和 hemoglobin-acid protease 的活性，IC50 值分别为 4.5 nM，6.2 nM，150 nM，290 nM，520 nM 和 260 nM。
M19987	2-Iodoacetamide	2-碘乙酰胺	Animal Modeling
	Iodoacetamide； IA；IAM
	2-Iodoacetamide（2-碘乙酰胺）是一种烷基化剂，通常在蛋白质组学样品制备过程中用于半胱氨酸的烷基化。可用于构建功能性消化不良动物模型。
M20458	Tabersonine hydrochloride	Tabersonine hydrochloride	Amyloid
M20458	Tabersonine, an ingredient extracted from the bean of Voacanga africana, is a potent inhibitor against Aβ(1?42) aggregation and toxicity.
M30647	Mechercharmycin A	Mechercharmycin A	Apoptosis
M30647	Mechercharmycin A 是一种从海洋来源的 Thermoactinomyces sp. YM3-251 分离出的细胞毒性物质。Mechercharmycin A 具有较强的抗肿瘤活性。
M55314	Recombinant Mouse Decorin Protein (HEK293, C-6His)	重组小鼠Decorin 蛋白 (HEK293, C-6His)	Cytokines and Growth Factors
	DCN
	Decorin (DCN) is a secreted chondroitin/dermatan sulfate proteoglycan in the family of small leucine-rich proteoglycans (SLRPs). Decorin regulates assembly of the extracellular collagen matrix and the bioactivity of the matrix associated growth factors such as FGF2, GDF8/Myostatin, TGFβ and WISP1. It also binds and activates EGFR, ErbB4 and IGFI-R.
M52606	Oxaloacetate decarboxylase	Oxaloacetate decarboxylase	Metabolite/Endogenous Metabolite
M52606	Oxaloacetate decarboxylase 催化草酰乙酸不可逆脱羧生成丙酮酸和COIC2。
M53203	ALX 40-4C	ALX 40-4C	CXCR
M53203	ALX 40-4C 是一种趋化因子受体 (CXCR4) 抑制剂，能够抑制 SDF-1 与 CXCR4 结合，Ki 值为 1 μM，具有抗 HIV-1 作用；ALX 40-4C Trifluoroacetate 同时为 APJ 受体拮抗剂，IC50 值为 2.9 μM。
M53905	Phe-Met-Arg-Phe amide trifluoroacetate	Phe-Met-Arg-Phe amide trifluoroacetate	Potassium Channel
M53905	Phe-Met-Arg-Phe amide trifluoroacetate 是一种神经肽，在肽能神经元中激活 K+ 电流，ED50 为 23 nM，这种作用具有剂量依赖性。
M55024	Recombinant Human DPP4/CD26 (HEK293, C-6His)	重组人DPP4/CD26 (HEK293, C-6His)	Cytokines and Growth Factors
	Dipeptidyl Peptidase 4; DPP IV; ADCP-2
	DPP4/CD26 is a signal-anchor for type II membrane protein that belongs to the peptidase S9B family. DPP4/CD26 acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. It’s binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner.
M55312	Recombinant Human Decorin Protein (HEK293, C-6His)	重组人Decorin 蛋白 (HEK293, C-6His)	Cytokines and Growth Factors
	DCN
	Decorin (DCN) is a secreted chondroitin/dermatan sulfate proteoglycan in the family of small leucine-rich proteoglycans (SLRPs). Decorin regulates assembly of the extracellular collagen matrix and the bioactivity of the matrix associated growth factors such as FGF2, GDF8/Myostatin, TGFβ and WISP1. It also binds and activates EGFR, ErbB4 and IGFI-R.
M55313	Recombinant Human Decorin Protein (HEK293)	重组人Decorin 蛋白 (HEK293)	Cytokines and Growth Factors
	DCN
	Decorin (DCN) is a secreted chondroitin/dermatan sulfate proteoglycan in the family of small leucine-rich proteoglycans (SLRPs). Decorin regulates assembly of the extracellular collagen matrix and the bioactivity of the matrix associated growth factors such as FGF2, GDF8/Myostatin, TGFβ and WISP1. It also binds and activates EGFR, ErbB4 and IGFI-R.

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