找到约 5 条 “Mitogen-activated protein kinase 1” 相关结果 （用时 0.303 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
| M52815 | Mitogen-activated protein kinase 1 | Mitogen-activated protein kinase 1 | NF-κB |
| Mitogen-activated protein kinase 1 (MAPK1) 可以激活下游 p38/NF-κB 通路。 | |||
| M8200 | SB 220025 trihydrochloride | SB 220025 trihydrochloride | Others |
| SB 220025 is a potent, specific inhibitor of human p38 mitogen-activated protein (MAP) kinase, with an IC50 value of 60 nM and 50- to 1000-fold selectivity. | |||
| M20176 | WAY-382818 | WAY-382818 | Others |
| WAY-382818 has mitogen-activated protein kinase phosphatase-1 inhibitory activity. | |||
| M20713 | DMX-5084 | DMX-5084 | MAPKAPK2/MAP3K/MAP4K |
| DMX-5804 is a potent, orally active and selective inhibitor of Mitogen-activated protein kinase kinase kinase kinase-4 (MAP4K4) with IC50 of 3 nM for human MAP4K4. DMX-5804 is more potent on human MAP4K4 with pIC50 of 8.55 than MINK1/MAP4K6 and TNIK/MAP4K7 with pIC50 of 8.18 and 7.96, respectively. | |||
| M20734 | (E/Z)-BCI | (E/Z)-BCI | Phosphatase |
| BCI, NSC 150117 | |||
| (E/Z)-BCI (BCI, NSC 150117) is an inhibitor of dual specific phosphatase 1/6 (DUSP1/DUSP6) and mitogen-activated protein kinase with EC50 of 13.3 μM and 8.0 μM for DUSP6 and DUSP1 in cells, respectively. (E)-BCI induces apoptosis via generation of reactive oxygen species (ROS) and activation of intrinsic mitochondrial pathway in H1299 lung cancer cells. | |||