找到约 5 条 “MET kinase-IN-4” 相关结果 （用时 0.32 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
| M30821 | MET kinase-IN-4 | MET kinase-IN-4 | c-Met |
| MET kinase-IN-4 是一种 Met 激酶抑制剂，具有口服活性。MET kinase-IN-4 具有有效的 Met 激酶抑制活性，IC50 值为 1.9 nM。MET kinase-IN-4 可用于癌症研究。 | |||
| M20606 | SAR125844 | SAR125844 | c-Met |
| SAR125844 is a potent intravenously active and highly selective MET kinase inhibitor, displaying nanomolar activity against the wild-type kinase (IC50 value of 4.2 nmol/L) and H1094Y, Y1235D, M1250T, L1195V, and D1228H kinase domain mutants (IC50 values of 0.22, 1.7, 6.5, 65, and 81 nmol/L, respectively). | |||
| M20652 | JNJ-38877618 | JNJ-38877618 | c-Met |
| JNJ-38877618 (OMO-1) is a potent, highly selective, orally bioavailable MET kinase inhibitor with binding affinity (Kd) of 1.4 nM and enzyme inhibitory activity against wt and M1268T mutant MET (2 and 3 nM IC50). | |||
| M20743 | AMG-1 | AMG-1 | c-Met |
| c-Met/RON Dual Kinase Inhibitor, RON-IN-1 | |||
| AMG-1 (c-Met/RON Dual Kinase Inhibitor, RON-IN-1) is a potent inhibitor of human c-Met and RON with IC50 of 4 nM and 9 nM, respectively. | |||
| M57192 | MET kinase-IN-2 | MET kinase-IN-2 | c-Met |
| MET kinase-IN-2 是一种有效的选择性的，具有口服活性的 MET 激酶抑制剂，IC50 值为 7.4 nM。MET kinase-IN-2 具有抗肿瘤活性。 | |||