找到约 7 条 “LYP-IN-3” 相关结果 （用时 0.109 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
| M42537 | LYP-IN-3 | LYP-IN-3 | Phosphatase |
| LYP-IN-3 是淋巴酪氨酸磷酸酶 (LYP) 的选择性抑制剂 (Ki=0.93 μM)，在肿瘤进展中调节 T 细胞受体 (TCR) 信号通路。 | |||
M40855
|
Recombinant Human Siglec-7 Protein (HEK293, C-6His) | 重组人Siglec-7蛋白 (HEK293, C-6His) | Receptor Proteins |
| sialic acid binding Ig-like lectin 7; CD328 antigen; p75/AIRM1; QA79 | |||
| Human Siglec-7 encodes a 467 amino acid (aa) polypeptide with a hydrophobic signal peptide, an N-terminal Ig-like V-type domain, two Ig-like C2-type domains, a transmembrane region and a cytoplasmic tail. It binds equally well to both alpha 2,3- and alpha 2,6-linked sialic acid. | |||
| M4363
|
Polyphyllin-VI | 重楼皂苷VI | Pyroptosis |
| Polyphyllin VI，一种活性皂甙，具有抗癌活性。Polyphyllin VI 诱导 G2/M 细胞周期停滞并引发细胞凋亡（apoptosis）。Polyphyllin VI 通过诱导非小细胞肺癌中的 ROS/NF-κB/NLRP3/GSDMD 信号轴来诱导 caspase-1 介导的细胞焦亡 (pyroptosis)。 | |||
| M4364
|
Paris saponin VII | 重楼皂苷 VII | Akt |
| Chonglou Saponin VII | |||
| Polyphyllin VII（重楼皂苷VII）是一种从Rhizoma paridis 中提取的甾体皂苷类化合物，它通过诱导细胞凋亡、自噬和铁死亡等多种方式抑制肿瘤细胞的增殖，以及通过调节EGFR-MEK/ERK信号通路来抑制肺癌细胞的转移，此外，它对Akt/p38 MAPK 和 P-gp也具有抑制活性。Polyphyllin VII还具有抗炎、抗纤维化和免疫调节等多种生物学活性。 | |||
| M25536
|
Recombinant Human CXCL13/BCA-1 (E. coli) | 重组人CXCL13/BCA-1蛋白 (E. coli) | Cytokines and Growth Factors |
| CXC chemokine BLC; Small-inducible cytokine B13 | |||
| CXCL13, also known as B-lymphocyte chemoattractant (BLC), is a CXC chemokine that is constitutively expressed in secondary lymphoid organs. Recombinant human CXCL13 is a single non-glycosylated polypeptide chain containing 87 amino acids and mature human BCA-1 shares 64 % amino acid sequence similarity with the murine protein and 23–34 % amino acid sequence identity with other known CXC chemokines. Determined by a chemotaxis bioassay using human B cells, the biological activity is in a concentration range of 1.0-10 ng/ml. | |||
| M42546 | LYP-IN-4 | LYP-IN-4 | Phosphatase |
| LYP-IN-4 是淋巴酪氨酸磷酸酶 (LYP) 的可逆和特异性的抑制剂 (Ki=1.34 μM，IC50=3.52μM)。 | |||
| M53015 | Pancreatic Polypeptide, bovine | Pancreatic Polypeptide, bovine | Neuropeptide Receptor |
| Pancreatic Polypeptide, bovine 是由 36 个氨基酸组成的直链多肽，由胰腺中产生，能够抑制由分泌素和胆囊素诱导的胰腺分泌。 | |||
