找到约 10 条 “Histone demethylase” 相关结果 （用时 0.108 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
M6143
|
SP2509 | SP2509 | Histone demethylase |
| HCI-2509 | |||
| SP2509是一种选择性histone demethylase LSD1抑制剂，SP2509 也是有效，选择性的 LSD1 拮抗剂，IC50为 13 nM，对MAO-A，MAO-B，乳酸脱氢酶和葡萄糖氧化酶没有活性。 | |||
| M6259
|
CP2 | CP2 | Histone demethylase |
| CP2是一种环肽，能够抑制JmjC histone demethylases KDM4，对KDM4A和KDM4C的IC50分别为42 nM和29 nM。 | |||
| M8299 | Methylstat | 甲基司他 | Others |
| Methylstat（甲基司他）是一种有效的组蛋白去甲基化酶（histone demethylases）抑制剂，可增加H3K27甲基化水平。它还具有抑制增殖、诱导凋亡以及诱导胞周期停滞等多种活性。 | |||
| M9526
|
GSK-J5 | GSK-J5 | Histone demethylase |
| GSK J5 | |||
| GSK-J5 is a cell-permeable, inactive control for histone demethylase JMJD3/UTX inhibitor GSK-J4. | |||
| M20864 | L-2-Hydroxyglutaric acid disodium | L-2-Hydroxyglutaric acid disodium | Histone demethylase |
| (S)-2-Hydroxyglutaric acid disodium, L-2-Hydroxyglutarate disodium, LGA, L-2HG | |||
| L-2-Hydroxyglutaric acid disodium ((S)-2-Hydroxyglutaric acid disodium, L-2-Hydroxyglutarate disodium, LGA, L-2HG) is an epigenetic modifier and a putative oncometabolite in kidney cancer that inhibits histone demethylases and hence promotes histone methylation. L-2-Hydroxyglutaric acid disodium is also an inhibitor of mitochondrial creatine kinase (Mi-CK) with Km and Ki of 2.52 mM and 11.13 mM, respectively. | |||
| M21329
|
Histone H2A (1-20) | Histone H2A (1-20) | Peptides |
| Histone H2A (1-20) 是一种含 35 个氨基酸的组蛋白 H2A 肽片段，是甲基转移酶/脱甲基酶 (methyltransferase/demethylase enzymes) 的底物。序列：Ser-Gly-Arg-Gly-Lys-Gln-Gly-Gly-Lys-Ala-Arg-Ala-Lys-Ala-Lys-Thr-Arg-Ser-Ser-Arg。 | |||
| M29846 | α-Hydroxyglutaric acid | α-Hydroxyglutaric acid | Histone demethylase |
| 2-Hydroxyglutarate; 2-Hydroxyglutaric acid; 2-Hydroxypentanedioic acid | |||
| α-Hydroxyglutaric acid (2-Hydroxyglutarate) 是戊二酸的 α-羟基酸形式。α-Hydroxyglutaric acid 是多种 α-酮戊二酸依赖性双加氧酶 (包括 histone demethylases 和 5-甲基胞嘧啶羟化酶 (5-methlycytosine (5mC) hydroxylases) 的 TET 家族) 的竞争性抑制剂。 | |||
| M30059 | α-Hydroxyglutaric acid disodium | α-Hydroxyglutaric acid disodium | Histone demethylase |
| 2-Hydroxyglutarate disodium; 2-Hydroxyglutaric acid disodium; 2-Hydroxypentanedioic acid disodium | |||
| α-Hydroxyglutaric acid (2-Hydroxyglutarate) disodium 是戊二酸的 α-羟基酸形式。α-Hydroxyglutaric acid disodium 是多种 α-酮戊二酸依赖性双加氧酶 (包括 histone demethylases 和 5-甲基胞嘧啶羟化酶 (5-methlycytosine (5mC) hydroxylases) 的 TET 家族) 的竞争性抑制剂。 | |||
| M58780
|
Recombinant Human KDM5A (E.Coli) | 重组人KDM5A (E.Coli) | Target Proteins |
| Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20' | |||
| M58781
|
Recombinant Human KDM6B (E.Coli) | 重组人KDM6B (E.Coli) | Target Proteins |
| Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code | |||
