找到约 4 条 “HMGB1-IN-1” 相关结果 （用时 0.698 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
| M41991 | HMGB1-IN-1 | HMGB1-IN-1 | HMGB1 |
| HMGB1-IN-1 能抑制 HMGB1/NF-κB/NLRP3 通路，同时可在 RAW264.7 细胞中表现出强烈的 NO 抑制作用，IC50 值为 15.9 ± 0.6 μM。具有抗炎活性。 | |||
M3571
|
Ammonium Glycyrrhizinate | 甘草酸单铵盐 | HMGB1 |
| AMGZ, Glycyram | |||
| Ammonium Glycyrrhizinate是来自甘草的特有产物，具有极高的甜味。Ammonium Glycyrrhizinate 是 HMGB1 的直接抑制剂，Ammonium Glycyrrhizinate 通过抑制HMGB1的水平，可以显著降低自噬的有效生物标志物LC3和Beclin-1蛋白的表达。Ammonium Glycyrrhizinate 具有抗炎、抗肿瘤、抗糖尿病的作用。 | |||
| M55397
|
Recombinant Human HMGB1 Protein (E. coli) | 重组人HMGB1 蛋白 (E. coli) | Other Proteins |
| High Mobility Group Protein B1 | |||
| High mobility group protein B1 is a member of the HMGB family consisting of three members, HMGB1, HMGB2 and HMGB3. As a nuclear protein, HMGB1 stabilizes nucleosomes and allows bending of DNA that facilitates gene transcription which is essential for individual survival. Meanwhile, it is revealed that HMGB1 can also act as a cytokine extracellularlly and regulates monocyte, T cell, dendritic cell activities in inflammatory responses. | |||
| M42898 | HMGB1-IN-2 | HMGB1-IN-2 | HMGB1 |
| HMGB1-IN-2 是高度保守的核蛋白 HMGB1 的抑制剂，在 RAW264.7 细胞中显示出 NO 抑制作用，IC50 值为 20.2 μM。 | |||
