找到约 31 条 “5-HT Receptor” 相关结果 （用时 0.114 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
| M41730 | 5-HT2A receptor agonist-3 | 5-HT2A receptor agonist-3 | 5-HT Receptor |
| 5-HT2A receptor agonist-3 是目前发现选择性最强的人类5-HT2A receptor 激动剂，Ki 值为 2.5 nM，对5-HT2A 的选择性是结构相似的5-HT2A receptor的124倍。 | |||
M3320
|
Quetiapine Fumarate | 富马酸喹硫平 | 5-HT Receptor |
| Quetiapine hemifumarate | |||
| Quetiapine Fumarate是一种 5-HT 受体激动剂，对人 5-HT1A 的 pEC50 值为 4.77。Quetiapine hemifumarate 是多巴胺受体 (dopamine receptor) 拮抗剂，对人 D2 的 pIC50 值为 6.33。 | |||
| M3675
|
Rotigotine | 罗替戈汀 | Dopamine Receptor |
| N-0923; (-)-N 0437 | |||
| Rotigotine (N-0437; N-0923) 是 dopamine receptor 激动剂，是 5-HT1A receptor 的部分激动剂，以及 α2B-adrenergic receptor 的拮抗剂，Ki 值分别为 0.71 nM (dopamine D3 receptor)，4-15 nM (D2，D5，D4 receptors)，83 nM (dopamine D1 receptor)。 | |||
| M3818
|
Rotigotine Hydrochloride | 罗替戈汀盐酸盐 | Dopamine Receptor |
| Rotigotine HCl;N-0923 Hydrochloride | |||
| Rotigotine Hydrochloride (N-0923 Hydrochloride) 是 dopamine receptor 纯激动剂，是 5-HT1A receptor 的部分激动剂，以及 α2B-adrenergic receptor 的拮抗剂，Ki 值分别为 0.71 nM (dopamine D3 receptor)，4-15 nM (D2，D5，D4 receptors)，83 nM (dopamine D1 receptor)。 | |||
| M1574
|
Iloperidone | 伊潘立酮 | 5-HT Receptor |
| HP873 | |||
| Iloperidone是一种dopamine (D2)/serotonin (5-HT2) receptor抑制剂，用于研究精神分裂症。 | |||
| M1565
|
Quetiapine sulfoxide | 喹硫平硫氧化物；喹硫平亚砜 | 5-HT Receptor |
| Quetiapine sulfoxide; Quetiapine S-oxide | |||
| Quetiapine sulfoxide是一种 5-HT 受体激动剂，对人 5-HT1A 的 pEC50 值为 4.77。Quetiapine hemifumarate 是多巴胺受体 (dopamine receptor) 拮抗剂，对人 D2 的 pIC50 值为 6.33。 | |||
| M1564
|
Quetiapine Sulfone | 喹硫平砜 | 5-HT Receptor |
| Quetiapine Sulfone是一种 5-HT 受体激动剂，对人 5-HT1A 的 pEC50 值为 4.77。Quetiapine hemifumarate 是多巴胺受体 (dopamine receptor) 拮抗剂，对人 D2 的 pIC50 值为 6.33。 | |||
| M4887
|
Pardoprunox Hydrochloride | 盐酸帕多芦诺 | 5-HT Receptor |
| SLV-308 | |||
| Pardoprunox hydrochloride (DU-126891, SME-308)是一种有效的部分 dopamine D2 receptor 的激动剂，对应的pEC50值为8.0，也是诱导 [35S]GTPγS binding 的部分激动剂，对应的pEC50值为9.2，和 serotonin 5-HT1A receptor 的激动剂，pEC50值为6.3。 | |||
| M5022
|
Almotriptan Malate | 阿莫曲普坦苹果酸盐 | 5-HT Receptor |
| LAS 31416 | |||
| Almotriptan Malate is a 5-HT1B/1D-receptor agonist used for the research of migraine. | |||
| M5835
|
Ondansetron Hydrochloride Dihydrate | 盐酸昂丹司琼二水合物 | 5-HT Receptor |
| GR 38032; SN 307; NSC 665799 | |||
| Ondansetron是一种高度特异的、选择性血清素5-HT3 receptor拮抗剂（Ki=6.16 nM），对多巴胺受体具有较低的亲和力。 | |||
| M5920
|
Ramosetron HCl | 盐酸雷莫司琼 | 5-HT Receptor |
| YM060 | |||
| Ramosetron Hydrochloride (盐酸雷莫司琼; YM060 Hydrochloride) is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting. | |||
| M6064
|
Ziprasidone HCl | 盐酸齐拉西酮 | 5-HT Receptor |
| CP-88059 | |||
| Ziprasidone HCl 是一类有效的Dopamine 和 Serotonin (5-HT) Receptor的拮抗剂，可用于精神分裂症以及双向性障碍的相关研究。 | |||
| M6425 | Altanserin hydrochloride | 阿坦色林盐 | Others |
| Altanserin hydrochloride is a 5-HT 2A receptor antagonist. | |||
| M6639 | Cyanopindolol hemifumarate | Cyanopindolol hemifumarate | Others |
| Cyanopindolol hemifumarate is a 5-HT1A/1B antagonist with roughly equal affinity at each receptor; also a β-adrenoceptor antagonist. | |||
| M6950 | Mesulergine hydrochloride | Mesulergine hydrochloride | Others |
| Mesulergine hydrochloride is a 5-HT 2A and 5-HT 2C antagonist. Also dopamine receptor partial agonist. | |||
| M7213 | Roxindole hydrochloride | Roxindole hydrochloride | Others |
| Roxindole hydrochloride is a dopamine D 2 autoreceptor agonist. Also has affinity for D 3, D 4, 5-HT 1A receptors and the 5-HT transporter. | |||
| M7284 | SDZ 205-557 hydrochloride | SDZ 205-557 hydrochloride | Others |
| SDZ 205-557 hydrochloride is a 5-HT 4/5-HT 3 receptor antagonist. | |||
| M7687 | CGS-12066 maleate salt | CGS-12066 maleate salt | Others |
| 5-HT1B serotonin receptor agonist. | |||
| M7763
|
Diacylglycerol Kinase Inhibitor I | Diacylglycerol Kinase Inhibitor I | 5-HT Receptor |
| R 59-022; DKGI-I | |||
| Diacylglycerol Kinase Inhibitor I（R 59-022）是一种二酰甘油激酶（DGK）和5-HT Receptor的抑制剂，作用于DGK的IC50值为2.8 µM，并能抑制 OAG 磷酸化为 OAPA。此外，Diacylglycerol Kinase Inhibitor I也能激活蛋白激酶 C (PKC)。 | |||
| M7900 | LP44 | LP44 | Others |
| LP44 is a high affinity 5-HT7 receptor agonist. | |||
| M7904 | Methiothepin mesylate salt | 马来酸甲硫替平 | Others |
| Metitepine mesylate; Ro 8-6837 mesylate | |||
| Methiothepin mesylate salt is a 5-HT1, 5-HT6, 5-HT7 serotonin receptor antagonist, which blocks serotonin autoreceptors. | |||
| M7935 | ML 10302 | ML 10302 | Others |
| Potent, selective 5-HT4 serotonin receptor agonist. | |||
| M7977 | Octoclothepin maleate salt | Octoclothepin maleate salt | Others |
| Octoclothepin maleate salt is a D2 dopamine receptor antagonist; 5-HT2 serotonin receptor antagonist. | |||
| M7984 | Opipramol dihydrochloride | 恶丙嗪 | Others |
| σ1/σ2 opioid receptor agonist; an antagonist at D2, 5HT2 and H1 receptors; atypical antidepressant, antipsychotic and anxiolytic. | |||
| M8009 | Pipamperone dihydrochloride | Pipamperone dihydrochloride | Others |
| D2 dopamine receptor antagonist; 5-HT2 serotonin receptor antagonist; antipsychotic. | |||
| M8145 | Ro4368554 | Ro4368554 | Others |
| Ro4368554 is a 5-HT6 receptor antagonist. | |||
| M8148 | LY-165,163 | LY-165,163 | Others |
| Selective 5-HT1A serotonin receptor agonist and 5-HT1D serotonin receptor antagonist. | |||
| M8158 | SDZ-205,557 hydrochloride | SDZ-205,557 hydrochloride | Others |
| Potent, selective 5-HT4 serotonin receptor antagonist. | |||
| M8167 | SB-204070 hydrochloride | SB-204070 hydrochloride | Others |
| Selective 5-HT4 serotonin receptor antagonist. | |||
| M8175 | SF-22 | SF-22 | Others |
| Radioligand studies reveal that SF-22 also targets 5-HT2B and 5-HT6 serotonin receptors and dopamine transporter. | |||
| M8176 | S15535 | S15535 | Others |
| Potent, orally active, partial 5-HT1A receptor agonist. | |||
