找到约 2 条 “499-44-5” 相关结果 （用时 0.206 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
M9140
|
Hinokitiol | 桧木醇；日柏醇；扁柏酚 | Keap1-Nrf2 |
| β-thujaplicin | |||
| Hinokitiol (β-thujaplicin)是从日本扁柏中分离到的挥发油成分，能够降低 Nrf2 的表达，减少 DNMT1 和 UHRF1 的 mRNA 和蛋白的表达，具有抗感染、抗氧化及抗肿瘤等活性。 | |||
| M21035 | LCH-7749944 | LCH-7749944 | PAK |
| GNF-PF-2356 | |||
| LCH-7749944 (GNF-PF-2356) is a novel and potent p21-activated kinase 4 (PAK4) inhibitor with an IC50 of 14.93 μM and has less potently inhibitory effect against PAK1, PAK5 and PAK6. LCH-7749944 causes successful inhibition of EGFR activity due to its inhibitory effect on PAK4. | |||
