找到约 1 条 “(E/Z)-BCI” 相关结果 (用时 0.562 秒)
目录号 | 产品名称 | 中文名称 | 靶点 |
---|---|---|---|
M20734 | (E/Z)-BCI | (E/Z)-BCI | Phosphatase |
BCI, NSC 150117 | |||
(E/Z)-BCI (BCI, NSC 150117) is an inhibitor of dual specific phosphatase 1/6 (DUSP1/DUSP6) and mitogen-activated protein kinase with EC50 of 13.3 μM and 8.0 μM for DUSP6 and DUSP1 in cells, respectively. (E)-BCI induces apoptosis via generation of reactive oxygen species (ROS) and activation of intrinsic mitochondrial pathway in H1299 lung cancer cells. |