Recombinant Mouse MIF Protein (E.coli, C-6His)  别名:Macrophage migration inhibitory factor; DER6; 重组小鼠MIF蛋白 (E.coli, C-6His)

目录号 M40641

Macrophage migration inhibitory factor (MIF) is a secreted protein and belongs to the MIF family. MIF is an important regulator of innate immunity. The circulating MIF binds to CD74 on other immune cells to trigger an acute immune response. Hence MIF is classified as an inflammatory cytokine. Furthermore glucocorticoids also stimulate white blood cells to release MIF and hence MIF partially counter acts the inhibitory effects that glucocorticoids have on the immune system. Finally trauma activates the anterior pituitary gland to release MIF.

Recombinant Mouse MIF Protein (E.coli, C-6His)结构式

 

规格 价格 库存状态
10ug ¥ 1800 现货
50ug ¥ 4500 现货
*AbMole所有产品仅供有资质的科研机构或医药企业进行科学研究或药证申报用途,不能被用于人体和任何其它用途。我们不向任何个人或非科研性质的机构提供产品和服务。
质量标准及产品资料
  • 纯度:>95%, Endotoxin < 1 EU/µg
  • COA
化学性质/溶解性/储存
性状 Lyophilized powder
中文名称 重组小鼠MIF蛋白 (E.coli, C-6His)
溶解性 Dissolve the lyophilized protein in distilled water. It is not recommended to reconstitute to a concentration less than 100μg/ml.
储存条件 Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at ≤ -20°C for 3 months.
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
生物活性

Macrophage migration inhibitory factor (MIF) is a secreted protein and belongs to the MIF family. MIF is an important regulator of innate immunity. The circulating MIF binds to CD74 on other immune cells to trigger an acute immune response. Hence MIF is classified as an inflammatory cytokine. Furthermore glucocorticoids also stimulate white blood cells to release MIF and hence MIF partially counter acts the inhibitory effects that glucocorticoids have on the immune system. Finally trauma activates the anterior pituitary gland to release MIF.

Recombinant Mouse MIF Protein expressed the target gene encoding Pro2-Ala115, with a 6His tag at the C-terminus.


Accession: P34884

Apparent Molecular Weight: 10-14 KDa, reducing conditions

Endotoxin < 1 EU/µg

Lyophilized from a 0.2 μm filtered solution of PBS, 0.02% Tween 80, 4.0% Mannitol, 4.0% Sucrose, pH7.4.

实验参考
动物实验

建议您制定动物给药及实验方案时,尽量参考已发表的相关实验文献(溶剂种类及配比众多,简单地溶解目的化合物,并不能解决动物给药依从性、体内生物利用度、组织分布等相关问题,未必能保证目的化合物在动物体内充分发挥生物学效用)。
体内实验的工作液,建议您现用现配,当天使用;如在配制过程中出现沉淀、析出现象,可以通过超声和(或)加热的方式助溶。
切勿一次性将产品全部溶解。


动物实验方案计算器

请在下面的计算器中,输入您的动物实验相关数据并点击计算,即可得到该实验的总需药量和工作液终浓度。
例如您给药剂量是10 mg/kg,平均每只动物的体重为20 g,每只动物的给药体积是100 μL,动物数量为20只,则该动物实验的总需药量为4 mg,工作液终浓度为2 mg/mL。

mg/kg
uL
该动物实验的总需药量为 mg
工作液终浓度2 mg/mL

1:鉴于实验过程的损耗,建议您至少多配1-2只动物的量;
2:为该产品最终给药时的浓度。






关键词:Recombinant Mouse MIF Protein (E.coli, C-6His), Macrophage migration inhibitory factor; DER6, Recombinant Mouse MIF Protein (E.coli, C-6His)供应商, Cytokines and Growth Factors抑制剂, 购买Recombinant Mouse MIF Protein (E.coli, C-6His), Recombinant Mouse MIF Protein (E.coli, C-6His)溶解度, Recombinant Mouse MIF Protein (E.coli, C-6His)结构式







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