重组小鼠IL-6蛋白是一种多向性细胞因子,通过调节免疫和炎症反应,在宿主防御中发挥重要作用。通过使用7TD1细胞进行的生物测定中测得的ED50为 < 3.0 pg/ml。
别名:Interleukin-6; BSF-2; IFN-b2
白介素-6(IL-6),也被称为BSF-2、CDF和IFNB2,是一种多能细胞因子,参与促炎症和抗炎症反应。它主要由T细胞、巨噬细胞、单核细胞、内皮细胞和肌肉细胞产生。IL-6与IL-6受体(IL-6R)结合,引发IL-6R与GP130的结合,并通过JAK和STATs诱导信号转导。
白介素-6(IL-6)刺激B细胞分化和抗体产生、骨髓瘤和浆细胞肿瘤的生长以及神经细胞分化。它还作为一种肌动素,由肌肉细胞在肌肉收缩时产生,并释放到血液中以帮助分解脂肪和改善胰岛素抵抗。
通过使用7TD1细胞进行的生物测定中测得的ED50为 < 3.0 pg/ml。
蛋白编号:P08505
表观分子量:24~26 kDa,在还原条件下
Endotoxin <0.2 EU/μg
剂型描述:从 0.2 μm 过滤的 PBS 溶液中冻干。
性状 | Lyophilized powder |
溶解性(25°C) | Reconstitute the lyophilized powder in ddH2O or PBS to 100 μg/ml. |
储存条件 | Stable for up to 6 months at ≤ -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. |
运输方式 | 冰袋运输,根据产品的不同,可能会有相应调整。 |
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