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Recombinant Mouse IL-15RA (Mammalian, C-Fc) 重组小鼠IL-15RA 蛋白 (Mammalian, C-Fc)

目录号 M21448 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


重组小鼠白细胞介素15受体亚基α由哺乳动物表达系统产生,编码Gly33-Lys205的目标基因在c端带有Fc标签表达。蛋白编号:Q60819。

Recombinant Mouse IL-15RA (Mammalian, C-Fc)结构式

别名:Interleukin-15 receptor subunit alpha

规格 价格 库存状态
10ug ¥ 1200 中国库存现货
50ug ¥ 2640 中国库存现货
其他规格数量报价?

质量标准及产品资料
  • 纯度: >95%, Endotoxin<1 EU/µg
  • COA
  • MSDS
生物活性

种属:Mouse

表达系统:Mammalian

内毒素:LAL测试测得小于0.1 ng/µg (1eu /µg)

存储及稳定性:冻干蛋白应在< -20℃下保存,但在室温下可稳定保存3周。重组蛋白溶液可在4-7℃保存2-7天。重组样品的等分线在< -20°C下稳定3个月。

分子量:45.5 KDa


生物活性:小鼠白细胞介素-15受体亚单位α,也称为Il15ra,是一种高亲和力的白细胞介素-15受体。Il15ra作为异质三聚体与IL-2受体β和γ亚基(普通γ链或γ c)结合,启动信号转导。它可以发出顺式和反式信号,其中来自一个细胞子集的IL15R向表达il2rg的相邻细胞表达IL15。Il15ra在特殊细胞中表达,包括多种t细胞、B细胞和非淋巴细胞。人类的Il15ra与小鼠形式的受体有45%的氨基酸序列同源性。il - 15r α mRNA的8种异构体已经被鉴定出来,这是由涉及不同外显子的可选剪接事件引起的。

化学性质
溶解性(25°C) It is not recommended to reconstitute to a concentration less than 100μg/ml.
储存条件 粉末型式       -20°C   3年;4°C   2年
溶于溶剂       -80°C   6个月;-20°C   1个月
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
参考文献

[1] Yanli Pan, et al. Curr Mol Med. Schizophrenia Patient Shows a Rare Interleukin 15 Receptor alpha Variant Disrupting Signal Transduction

[2] Jesse Rowley, et al. Eur J Immunol. Expression of IL-15RA or an IL-15/IL-15RA fusion on CD8+ T cells modifies adoptively transferred T-cell function in cis

[3] Jesse Rowley, et al. J Immunol. Inhibition of tumor growth by NK1.1+ cells and CD8+ T cells activated by IL-15 through receptor beta/common gamma signaling in trans

[4] Xiaogang Du, et al. J Gene Med. The adjuvant effects of co-stimulatory molecules on cellular and memory responses to HBsAg DNA vaccination

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