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Recombinant Human UBE2D1 (E.coli, N-GST) 重组人UBE2D1蛋白 (E.coli, N-GST)

目录号 M22462 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


重组人UBE2D1由大肠杆菌表达系统产生,编码 Met1-Met147 的靶基因在 N 末端带有 GST 标签。泛素结合酶E2 D1(UBE2D1)属于泛素结合酶家族。泛素化至少涉及三类酶:泛素激活酶或 E1、泛素结合酶或 E2,以及泛素-蛋白质连接酶或 E3。

Recombinant Human UBE2D1 (E.coli, N-GST)结构式

别名:Ubiquitin-conjugating Enzyme E2 D1

规格 价格 库存状态
10ug ¥ 580 中国库存现货
50ug ¥ 1500 中国库存现货
其他规格数量报价?

质量标准及产品资料
  • 纯度: >95%, Endotoxin < 1 EU/µg
  • COA
  • MSDS
生物活性

重组人UBE2D1由大肠杆菌表达系统产生,编码 Met1-Met147 的靶基因在 N 末端带有 GST 标签。泛素结合酶E2 D1(UBE2D1)属于泛素结合酶家族。泛素化至少涉及三类酶:泛素激活酶或 E1、泛素结合酶或 E2,以及泛素-蛋白质连接酶或 E3。它还通过与 E1 泛素激活酶和 E3 泛素蛋白连接酶相互作用,在肿瘤抑制蛋白 p53 和缺氧诱导转录因子 HIF1alpha 的泛素化中发挥作用。


蛋白编号: P51668

表观分子量: 40 KDa,还原条件

剂型描述: 以 50mM HEPES、150mM NaCl、2mM DTT、10% 甘油的 0.2 μm 过滤溶液提供,pH 7.5。

该产品使用干冰包装运输。

化学性质
储存条件 Store at ≤-70°C, stable for 6 months after receipt
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
参考文献

[1] Matthew E R Maitland, et al. Sci Rep. The mammalian CTLH complex is an E3 ubiquitin ligase that targets its subunit muskelin for degradation

[2] Christine K Schmidt, et al. Nat Cell Biol. Systematic E2 screening reveals a UBE2D-RNF138-CtIP axis promoting DNA repair

[3] Jeong-Hoon Kim, et al. BMB Rep. Synergistic effect of two E2 ubiquitin conjugating enzymes in SCF(hFBH1) catalyzed polyubiquitination

[4] So Maezawa, et al. PLoS One. Ubiquitylation of terminal deoxynucleotidyltransferase inhibits its activity

[5] Alexander Espinosa, et al. Exp Cell Res. The autoantigen Ro52 is an E3 ligase resident in the cytoplasm but enters the nucleus upon cellular exposure to nitric oxide

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