基质细胞衍生因子-1β (SDF-1β),也被称为SCYB12, PBSF和CXCL12,是一个8.3 kDa,肝素结合的CXC(或α)趋化因子家族成员,通过CXCR4受体发出信号。Protein Construction:SDF-1β/CXCL12 (Lys22-Met93)。Accession # P48061。
别名:SDF1β; SDF-1 beta; CXCL-12
基质细胞衍生因子-1β (SDF-1β),也被称为SCYB12, PBSF和CXCL12,是一个8.3 kDa,肝素结合的CXC(或α)趋化因子家族成员,通过CXCR4受体发出信号。据报道,SDF-1α和β在中性pH和生理离子强度下是单体。在细胞表面,这可能很好地促进了SDF-1与其两个受体CXCR4和syndecan4的相互作用。已知硫酸肝素可以保护SDF-1不被蛋白质水解,CXCR4作为二聚体组成存在。在其众多功能中,已知CXCL12影响淋巴生成,调节神经祖细胞的模式和细胞数量,并促进血管生成(12,13)。它还能增强髓样祖细胞的存活。
The biological activity determined by a chemotaxis bioassay using PHA and rHuIL-2 activated human peripheral blood T-lymphocytes is in a concentration range of 20.0-80.0 ng/ml.
Accession: P48061
Theoretical Molecular Weight: 8.5 kDa
Endotoxin < 1 EU/μg
Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4.
性状 | Lyophilized powder |
溶解性(25°C) | Reconstitute the lyophilized powder in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/ml. |
储存条件 | Stable for up to 6 months at ≤ -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. |
运输方式 | 冰袋运输,根据产品的不同,可能会有相应调整。 |
其他相关的Recombinant Proteins产品 |
---|
Recombinant Human Serpin A12 (E.coli, N-GST)
Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin is also a unique insulin sensitizing adipocytokine in obesity. |
Recombinant Human B2M Protein (Mammalian, C-6His)
β-2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family. B2M may adopt the fibrillar configuration of amyloid in certain pathologic states. |
Recombinant Mouse E-Selectin/CD62E Protein (HEK293)
E-selectin, also known as endothelial leukocyte adhesion molecule-1 (ELAM-1) and CD62E, is an inducible adhesion molecule that is expressed on the surfaces of stimulated vascular endothelial cells and is sometimes involved in cancer cell metastasis. |
Recombinant Human DPP4/CD26 (Mammalian, C-6His)
DPP4/CD26 is a signal-anchor for type II membrane protein that belongs to the peptidase S9B family. DPP4/CD26 acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. It’s binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. |
Recombinant Human USP14 (E.coli, N-6His)
USP14 belongs to the ubiquitin-specific processing (USP) family which is a deubiquitinating enzyme (DUB) with His and Cys domains. USP14 acts also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. |
产品仅供科学研究或药证申报的用途使用,不为任何个人或者非科研性质的其他用途提供服务。
Copyright © 2010-2022 AbMole版权所有 沪ICP备16047849号 沪公网安备 31011502012228号