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Recombinant Human SDF-1β/CXCL12 (E. coli) 重组人SDF-1β/CXCL12 蛋白 (E. coli)

目录号 M21429 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


基质细胞衍生因子-1β (SDF-1β),也被称为SCYB12, PBSF和CXCL12,是一个8.3 kDa,肝素结合的CXC(或α)趋化因子家族成员,通过CXCR4受体发出信号。Protein Construction:SDF-1β/CXCL12 (Lys22-Met93)。Accession # P48061。

Recombinant Human SDF-1β/CXCL12 (E. coli)结构式

别名:SDF1β; SDF-1 beta; CXCL-12

规格 价格 库存状态
10ug ¥ 3150 中国库存现货
其他规格数量报价?

质量标准及产品资料
  • 纯度: >97%, Endotoxin<1 EU/µg
  • COA
  • MSDS
生物活性

基质细胞衍生因子-1β (SDF-1β),也被称为SCYB12, PBSF和CXCL12,是一个8.3 kDa,肝素结合的CXC(或α)趋化因子家族成员,通过CXCR4受体发出信号。据报道,SDF-1α和β在中性pH和生理离子强度下是单体。在细胞表面,这可能很好地促进了SDF-1与其两个受体CXCR4和syndecan4的相互作用。已知硫酸肝素可以保护SDF-1不被蛋白质水解,CXCR4作为二聚体组成存在。在其众多功能中,已知CXCL12影响淋巴生成,调节神经祖细胞的模式和细胞数量,并促进血管生成(12,13)。它还能增强髓样祖细胞的存活。

The biological activity determined by a chemotaxis bioassay using PHA and rHuIL-2 activated human peripheral blood T-lymphocytes is in a concentration range of 20.0-80.0 ng/ml.


Accession: P48061

Theoretical Molecular Weight: 8.5 kDa

Endotoxin < 1 EU/μg

Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4.

化学性质
性状 Lyophilized powder
溶解性(25°C) Reconstitute the lyophilized powder in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/ml.
储存条件 Stable for up to 6 months at ≤ -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C.
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
参考文献

[1] Avital Mendelson, et al. FASEB J. Chondrogenesis by chemotactic homing of synovium, bone marrow, and adipose stem cells in vitro

[2] Yi Tan, et al. Cardiovasc Res. A novel CXCR4 antagonist derived from human SDF-1beta enhances angiogenesis in ischaemic mice

[3] Maria De La Luz Sierra, et al. Blood. Differential processing of stromal-derived factor-1alpha and stromal-derived factor-1beta explains functional diversity

[4] C Moriya, et al. FEBS Lett. Large quantity production with extreme convenience of human SDF-1alpha and SDF-1beta by a Sendai virus vector

[5] M J Hosie, et al. J Virol. Modulation of feline immunodeficiency virus infection by stromal cell-derived factor

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关键词:Recombinant Human SDF-1β/CXCL12 (E. coli), SDF1β; SDF-1 beta; CXCL-12, Recombinant Human SDF-1β/CXCL12 (E. coli)供应商, Recombinant Proteins抑制剂, 购买Recombinant Human SDF-1β/CXCL12 (E. coli), Recombinant Human SDF-1β/CXCL12 (E. coli)溶解度, Recombinant Human SDF-1β/CXCL12 (E. coli)结构式








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