重组人高迁移率族蛋白 1 (HMGB1)，也称为 HMG-1 或两性蛋白，是非组蛋白染色体蛋白的高迁移率族蛋白家族的成员。人 HMGB1 表达为包含三个结构域的 30 kDa、215 个氨基酸 (aa) 的单链多肽。
别名：High Mobility Group Box-1; rHuHMGB1
重组人高迁移率族蛋白 1 (HMGB1)，也称为 HMG-1 或两性蛋白，是非组蛋白染色体蛋白的高迁移率族蛋白家族的成员。人 HMGB1 表达为包含三个结构域的 30 kDa、215 个氨基酸 (aa) 的单链多肽。HMGB1 在几乎所有细胞中都以高水平表达。它最初被发现是一种可以弯曲 DNA 的核蛋白。
蛋白编号：P09429
分子量：约 26.0 kDa。
Endotoxin < 1 EU/μg
剂型描述：从 PBS 中的 0.2 μm 过滤溶液冻干，pH 7.4。
| 溶解性（25°C） | Reconstitute the lyophilized powder in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. |
| 储存条件 | Stored at ≤ -20°C, stable for up to 6 months after receipt. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. |
| 运输方式 | 冰袋运输，根据产品的不同，可能会有相应调整。 |
[4] Ben Lu, et al. Nature. Novel role of PKR in inflammasome activation and HMGB1 release
[5] A Tesniere, et al. Oncogene. Immunogenic death of colon cancer cells treated with oxaliplatin
| 其他相关的Recombinant Proteins产品 |
|---|
| Recombinant Mouse Lumican (Mammalian, C-6His)
Lumican binds to laminin. It has positive regulation of transcription from RNA polymerase II promoter and transforming growth factor beta1 production. |
| Recombinant Human Serpin A12 (E.coli, N-GST)
Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin is also a unique insulin sensitizing adipocytokine in obesity. |
| Recombinant Human B2M Protein (Mammalian, C-6His)
β-2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family. B2M may adopt the fibrillar configuration of amyloid in certain pathologic states. |
| Recombinant Mouse E-Selectin/CD62E Protein (HEK293)
E-selectin, also known as endothelial leukocyte adhesion molecule-1 (ELAM-1) and CD62E, is an inducible adhesion molecule that is expressed on the surfaces of stimulated vascular endothelial cells and is sometimes involved in cancer cell metastasis. |
| Recombinant Human DPP4/CD26 (Mammalian, C-6His)
DPP4/CD26 is a signal-anchor for type II membrane protein that belongs to the peptidase S9B family. DPP4/CD26 acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. It’s binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. |
产品仅供科学研究或药证申报的用途使用，不为任何个人或者非科研性质的其他用途提供服务。
Copyright © 2010-2022 AbMole版权所有 沪ICP备16047849号 沪公网安备 31011502012228号
蛋白质研究