Recombinant Human FGF-4 (E. coli) 重组人FGF-4蛋白（E. coli)

目录号 M21554 所有产品仅供科研使用，严禁用于人或动物的治疗等任何其他用途，不为任何个人提供产品和服务

成纤维细胞生长因子-4 (FGF-4)也被称为K-FGF，是FGF家族的一种肝素结合生长因子。它是由其致癌转化活性鉴定的。Accession # P08620。

别名：HBGF-4; HST; HST-1; HSTF1; K-FGF; KFGF

规格	价格	库存状态
5ug	¥ 1170	中国库存现货
25ug	¥ 1845	中国库存现货

其他规格数量报价？

质量标准及产品资料

纯度：＞95%, Endotoxin < 0.2 EU/μg
COA
MSDS

产品信息

生物活性

种属：Human

表达系统：E. coli

纯度：SDS-PAGE分析> 95%，高效液相色谱法分析> 95%

内毒素：凝胶凝血法测定蛋白含量< 0.2 EU/μg

表观分子量：~19.4 kDa，在SDS-PAGE还原条件下

存储及稳定性：收到后，本产品在低于-70°C的条件下可保持稳定长达6个月。重建后，产品应在4°C下稳定长达1周或在-20°C下稳定长达3个月。对于长期储存，建议添加载体蛋白(例如0.1% BSA)。避免反复冻融循环。

生物活性：ED50 < 0.5 ng/ml，在使用3T3细胞的细胞增殖试验中测量，对应于> 2.0 × 10⁶单位/mg的特异活性。成纤维细胞生长因子-4 (FGF-4)也被称为K-FGF，是FGF家族的一种肝素结合生长因子。它是由其致癌转化活性鉴定的。FGF-4和FGF-3位于11号染色体上。FGF-4及其受体(FGF R1c、2c、3c和4)在胚胎发育、细胞增殖和细胞分化的调控中发挥重要作用。FGF-4是胚胎发生过程中正常肢体和心脏瓣膜发育所必需的。

化学性质

溶解性（25°C）	It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O up to 100 μg/ml.
储存条件	粉末型式 -20°C 3年；4°C 2年溶于溶剂 -80°C 6个月；-20°C 1个月
运输方式	冰袋运输，根据产品的不同，可能会有相应调整。

参考文献

[1] Kotaro Hirai, et al. J Gene Med. Antisense oligodeoxynucleotide against HST-1/FGF-4 suppresses tumorigenicity of an orthotopic model for human germ cell tumor in nude mice

[2] Victoria Franke Stenport, et al. Clin Oral Implants Res. FGF-4 and titanium implants: a pilot study in rabbit bone

[3] No authors listed. BioDrugs. FGF-4 gene therapy GENERX--Collateral Therapeutics

[4] K A Lamb, et al. Mol Reprod Dev. NF-Y binds to the CCAAT box motif of the FGF-4 gene and promotes FGF-4 expression in embryonal carcinoma cells

[5] T Alanko, et al. Exp Cell Res. FGF-2 inhibits apoptosis in human teratocarcinoma cells during differentiation on collagen substratum

获取最新目录册

其他相关的Recombinant Proteins产品
Recombinant Mouse Lumican (Mammalian, C-6His) Lumican binds to laminin. It has positive regulation of transcription from RNA polymerase II promoter and transforming growth factor beta1 production.
Recombinant Human Serpin A12 (E.coli, N-GST) Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin is also a unique insulin sensitizing adipocytokine in obesity.
Recombinant Human B2M Protein (Mammalian, C-6His) β-2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family. B2M may adopt the fibrillar configuration of amyloid in certain pathologic states.
Recombinant Mouse E-Selectin/CD62E Protein (HEK293) E-selectin, also known as endothelial leukocyte adhesion molecule-1 (ELAM-1) and CD62E, is an inducible adhesion molecule that is expressed on the surfaces of stimulated vascular endothelial cells and is sometimes involved in cancer cell metastasis.
Recombinant Human DPP4/CD26 (Mammalian, C-6His) DPP4/CD26 is a signal-anchor for type II membrane protein that belongs to the peptidase S9B family. DPP4/CD26 acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. It’s binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner.

信号通路

产品类型

Recombinant Human FGF-4 (E. coli) 重组人FGF-4蛋白（E. coli)

目录号 M21554 所有产品仅供科研使用，严禁用于人或动物的治疗等任何其他用途，不为任何个人提供产品和服务

质量标准及产品资料

生物活性

化学性质

参考文献

AbMole

服务与支持

技术资源

联系我们