蛋白构造:编码人类CTSK (Ala115-Met329)的DNA序列与His标签融合。Accession #P43235。
别名:CTSK;Cathepsin K;Cathepsin O;Cathepsin O2
种属:Human
表达系统:E.coli
纯度:>90%由SDS-PAGE测定
预测分子量:25.81 kDa
存储及稳定性:使用手动解冻冰柜,避免重复冻融循环。在2 - 8°C保存一周。从收到之日起在-20至-80°C保存12个月。
生物活性:硫醇蛋白酶参与破骨细胞骨吸收,可能部分参与骨重塑紊乱。在酸性ph值下对纤维蛋白原显示出强大的内蛋白酶活性。可能在细胞外基质降解中发挥重要作用。在甲状腺滤泡腔内通过有限的TG/甲状腺球蛋白蛋白水解参与甲状腺激素甲状腺素(T4)的释放
溶解性(25°C) | Reconstitute in sterile water for a stock solution. |
储存条件 |
粉末型式 -20°C 3年;4°C 2年 溶于溶剂 -80°C 6个月;-20°C 1个月 |
运输方式 | 冰袋运输,根据产品的不同,可能会有相应调整。 |
[5] F Bhling, et al. Adv Exp Med Biol. Cathepsin K expression in human lung
其他相关的Recombinant Proteins产品 |
---|
Recombinant Human B2M Protein (Mammalian, C-6His)
β-2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family. B2M may adopt the fibrillar configuration of amyloid in certain pathologic states. |
Recombinant Mouse E-Selectin/CD62E Protein (HEK293)
E-selectin, also known as endothelial leukocyte adhesion molecule-1 (ELAM-1) and CD62E, is an inducible adhesion molecule that is expressed on the surfaces of stimulated vascular endothelial cells and is sometimes involved in cancer cell metastasis. |
Recombinant Human DPP4/CD26 (Mammalian, C-6His)
DPP4/CD26 is a signal-anchor for type II membrane protein that belongs to the peptidase S9B family. DPP4/CD26 acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. It’s binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. |
Recombinant Human USP14 (E.coli, N-6His)
USP14 belongs to the ubiquitin-specific processing (USP) family which is a deubiquitinating enzyme (DUB) with His and Cys domains. USP14 acts also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. |
Recombinant Human EpCAM/Trop-1 (Mammalian, C-Fc)
Epithelial Cell Adhesion Molecule (EpCAM) is a signal type I transmembrane glycoprotein. EpCAM plays a role in embryonic stem cells proliferation and differentiation; it up-regulates the expression of FABP5, MYC and Cyclin A and Cyclin E. It is highly and selectively expressed by undifferentiated embryonic stem cells. |
产品仅供科学研究或药证申报的用途使用,不为任何个人或者非科研性质的其他用途提供服务。
Copyright © 2010-2022 AbMole版权所有 沪ICP备16047849号 沪公网安备 31011502012228号