—更好的抑制剂,金标准的化合物库
致电  021-50967598
或联系  在线客服QQ

Recombinant Human C1QB Protein (Baculovirus-Insect, His Tag) 重组人C1QB蛋白 (Baculovirus-Insect, His Tag)

目录号 M22491 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


Complement Component 1, q subcomponent (C1q) associates with C1r and C1s in order to yield the first component of the serum complement system. Sequence comparison of C1q from three different species have shown that the B chains have the strongest similarity. The recombinant human C1QB consists of 237 amino acids with the predicted molecular mass of 25.2 kDa.

Recombinant Human C1QB Protein (Baculovirus-Insect, His Tag)结构式

别名:Complement Component 1, q subcomponent, B chain

规格 价格 库存状态
100ug ¥ 9495 中国库存现货
其他规格数量报价?

质量标准及产品资料
  • 纯度: >94%, Endotoxin < 1 EU/µg
  • COA
  • MSDS
生物活性

补体成分 1,q 亚成分 (C1q) 与 C1r 和 C1s 结合以产生血清补体系统的第一个成分。C1q 缺乏与红斑狼疮和肾小球肾炎有关。C1q 由 18 条多肽链组成:6 条 A 链、6 条 B 链和 6 条 C 链。脊椎动物染色体 DNA 的 Southern 印迹分析表明 C1qB 基因之间的相似性最高,其次是 C1qC,最后是 C1qA。来自三个不同物种的C1q的序列比较表明B链具有最强的相似性。重组人 C1QB 蛋白由 237 个氨基酸组成,预测分子量为 25.2 kDa。表达了编码人 C1QB (NP_000482.3) 前体 (Met 1-Ala 253) 的 DNA 序列,带有羧基末端多组氨酸标签。


剂型描述:从无菌 50mM Tris、100mM NaCl、10% 甘油、0.5mM TCEP、pH 7.5 中冻干。

化学性质
储存条件 Stable for up to twelve months from date of receipt at -20℃ to -80℃
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
参考文献

[1] Isabelle Bally, et al. J Immunol Methods. Functional recombinant human complement C1q with different affinity tags

[2] Hongyu Yuan, et al. Acta Crystallogr F Struct Biol Commun. Crystallization and preliminary crystallographic studies of the complement 1qA globular domain from zebrafish, Dare-C1qAgD

[3] Maria Radanova, et al. Immunobiology. Anti-C1q autoantibodies specific against the globular domain of the C1qB-chain from patient with lupus nephritis inhibit C1q binding to IgG and CRP

[4] Silvia Stojanov, et al. Proc Natl Acad Sci U S A. Periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) is a disorder of innate immunity and Th1 activation responsive to IL-1 blockade

[5] Yu-Lan Hu, et al. J Biol Chem. Characterization of C1q in teleosts: insight into the molecular and functional evolution of C1q family and classical pathway

100%好运必中
ChemBridge—化合物库中的金标准
  获取最新目录册
Abmole最新目录册
其他相关的Recombinant Proteins产品
Recombinant Mouse Lumican (Mammalian, C-6His)

Lumican binds to laminin. It has positive regulation of transcription from RNA polymerase II promoter and transforming growth factor beta1 production.

Recombinant Human Serpin A12 (E.coli, N-GST)

Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin is also a unique insulin sensitizing adipocytokine in obesity.

Recombinant Human B2M Protein (Mammalian, C-6His)

β-2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family. B2M may adopt the fibrillar configuration of amyloid in certain pathologic states.

Recombinant Mouse E-Selectin/CD62E Protein (HEK293)

E-selectin, also known as endothelial leukocyte adhesion molecule-1 (ELAM-1) and CD62E, is an inducible adhesion molecule that is expressed on the surfaces of stimulated vascular endothelial cells and is sometimes involved in cancer cell metastasis.

Recombinant Human DPP4/CD26 (Mammalian, C-6His)

DPP4/CD26 is a signal-anchor for type II membrane protein that belongs to the peptidase S9B family. DPP4/CD26 acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. It’s binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner.





关键词:Recombinant Human C1QB Protein (Baculovirus-Insect, His Tag), Complement Component 1, q subcomponent, B chain, Recombinant Human C1QB Protein (Baculovirus-Insect, His Tag)供应商, Recombinant Proteins抑制剂, 购买Recombinant Human C1QB Protein (Baculovirus-Insect, His Tag), Recombinant Human C1QB Protein (Baculovirus-Insect, His Tag)溶解度, Recombinant Human C1QB Protein (Baculovirus-Insect, His Tag)结构式








021-50967598      
2118621495      
inquiry@abmole.cn




产品仅供科学研究或药证申报的用途使用,不为任何个人或者非科研性质的其他用途提供服务。

Copyright © 2010-2022 AbMole版权所有    沪ICP备16047849号   沪公网安备 31011502012228号