重组人碱性成纤维细胞生长因子（bFGF）是成纤维细胞生长因子家族的一个成员，能够刺激中胚层来源的细胞、神经外胚层，外胚层和内胚层来源细胞的增殖。
别名：FGFB; FGF basic; HBGF-2; FGF2
重组人碱性成纤维细胞生长因子（bFGF）是成纤维细胞生长因子家族的一个成员，能够刺激中胚层来源的细胞、神经外胚层，外胚层和内胚层来源细胞的增殖。在体外，bFGF 对内皮细胞具有的趋化和促有丝分裂剂的作用，并且能够促进神经的分化，存活和再生。它已被证明是在调节胚胎发育和分化中至关重要的，它能在血管生成，组织修复，胚胎发育和神经元功能的体内调节中发挥作用。
用3T3细胞进行剂量依赖增殖试验测定，测得的ED50为≤0.1 ng/mL，对应的活性为≥1×107IU/mg。
预测的分子量为 17.1kD
Endotoxin <0.1EU/μg
Int J Biol Macromol. 2024 Feb 17;263(Pt 1):130287.
Fabrication of multifunctional silk nanofibril/hyaluronic acid scaffold for spinal cord repair
| 溶解性（25°C） | Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml. |
| 储存条件 | Stored at ≤-20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
| 运输方式 | 冰袋运输，根据产品的不同，可能会有相应调整。 |
| 其他相关的Recombinant Proteins产品 |
|---|
| Recombinant Rat FGF-basic (E. coli, Ala11-Ser154)
Fibroblast Growth Factor-basic (FGF-basic), also known as FGF-2, is a pleiotropic cytokine and one of the prototypic members of the heparin-binding FGF family. FGF-basic regulates a variety of processes including cell proliferation, differentiation, survival, adhesion, motility, apoptosis, limb formation and wound healing. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. |
| Recombinant Human HMGB1 Protein (E. coli)
High mobility group protein B1 is a member of the HMGB family consisting of three members, HMGB1, HMGB2 and HMGB3. As a nuclear protein, HMGB1 stabilizes nucleosomes and allows bending of DNA that facilitates gene transcription which is essential for individual survival. Meanwhile, it is revealed that HMGB1 can also act as a cytokine extracellularlly and regulates monocyte, T cell, dendritic cell activities in inflammatory responses. |
| Recombinant Human IL-25/IL-17E (E. coli, C-His)
Interleukin 25 (IL-25) belongs to the Interleukin 17 (IL-17) family of proteins. IL25 is a glycoprotein secreted as dimers by innate effector eosinophils and basophils, and present at very low levels in various peripheral tissues. IL25, together with IL17B, are ligands for the cytokine receptor IL17BR, and the cross-linking induces NF-κB activation and production of the proinflammatory chemokine IL-8, as well as ERK, JNK, and p38 activation. |
| Recombinant Human IL-25/IL-17E (Mammalian, C-6His)
Interleukin 25 (IL-25) belongs to the Interleukin 17 (IL-17) family of proteins. IL25 is a glycoprotein secreted as dimers by innate effector eosinophils and basophils, and present at very low levels in various peripheral tissues. IL25, together with IL17B, are ligands for the cytokine receptor IL17BR, and the cross-linking induces NF-κB activation and production of the proinflammatory chemokine IL-8, as well as ERK, JNK, and p38 activation. |
| Recombinant Human SEMA3A (Mammalian, N-6His-Flag)
Semaphorin 3A (SEMA3A) is a secreted protein which belongs to the semaphorin family. Semaphorin 3A can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. |
产品仅供科学研究或药证申报的用途使用，不为任何个人或者非科研性质的其他用途提供服务。
Copyright © 2010-2022 AbMole版权所有 沪ICP备16047849号 沪公网安备 31011502012228号
蛋白质研究