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Recombinant Human Adiponectin (CHO) 重组人Adiponectin蛋白 (CHO)

目录号 M15042 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


Adiponectin是一种重要的脂肪因子,参与控制脂肪代谢和胰岛素敏感性。它只由脂肪细胞合成,分泌到血浆中。蛋白构造:Acrp30 (Glu19-Asn244),Accession # :Q15848。

Recombinant Human Adiponectin (CHO)结构式

别名:Acrp-30; GBP-28; Apm-1

规格 价格 库存状态
10ug ¥ 1880 中国库存现货
50ug ¥ 4480 中国库存现货
其他规格数量报价?

质量标准及产品资料
  • 纯度: >95%, Endotoxin < 0.2 EU/μg
  • COA
  • MSDS
生物活性

Adiponectin 通过负向调控thf的表达来拮抗thf。Adiponectin 还通过camp依赖的途径抑制内皮NF-kappa-B信号。脂联素可以形成低分子量配合物(LMW)、中分子量配合物(MMW)和高分子量配合物(HMW)。它们与各种生长因子结合,如HBEGF、PDGFB和FGF2,并在细胞生长、血管生成和组织重塑中发挥作用。

通过用M1细胞生长抑制试验测定的ED50为 < 20.0 μg/ml。


Accession # Q15848

Endotoxin < 0.2 EU/μg

Apparent Molecular Weight: 25~28 kDa, reducing conditions

Lyophilized after extensive dialysis against PBS.

化学性质
性状 Lyophilized powder
溶解性(25°C) Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml.
储存条件 Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
参考文献

[1] Hiroshi Kataoka, et al. Neurol Sci. Serum adiponectin levels between patients with Parkinson's disease and those with PSP

[2] Zhongjie Fu, et al. EMBO Mol Med. Photoreceptor glucose metabolism determines normal retinal vascular growth

[3] Yoshiki Terashima, et al. J Orthop Surg Res. Expression of adiponectin receptors in human and rat intervertebral disc cells and changes in receptor expression during disc degeneration using a rat tail temporary static compression model

[4] Jun Wada. Expert Opin Investig Drugs. Vaspin: a novel serpin with insulin-sensitizing effects

[5] Ayanthi A Richards, et al. Mol Endocrinol. Adiponectin multimerization is dependent on conserved lysines in the collagenous domain: evidence for regulation of multimerization by alterations in posttranslational modifications

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