Adiponectin是一种重要的脂肪因子,参与控制脂肪代谢和胰岛素敏感性。它只由脂肪细胞合成,分泌到血浆中。蛋白构造:Acrp30 (Glu19-Asn244),Accession # :Q15848。
别名:Acrp-30; GBP-28; Apm-1
Adiponectin 通过负向调控thf的表达来拮抗thf。Adiponectin 还通过camp依赖的途径抑制内皮NF-kappa-B信号。脂联素可以形成低分子量配合物(LMW)、中分子量配合物(MMW)和高分子量配合物(HMW)。它们与各种生长因子结合,如HBEGF、PDGFB和FGF2,并在细胞生长、血管生成和组织重塑中发挥作用。
通过用M1细胞生长抑制试验测定的ED50为 < 20.0 μg/ml。
Accession # Q15848
Endotoxin < 0.2 EU/μg
Apparent Molecular Weight: 25~28 kDa, reducing conditions
Lyophilized after extensive dialysis against PBS.
性状 | Lyophilized powder |
溶解性(25°C) | Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml. |
储存条件 | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
运输方式 | 冰袋运输,根据产品的不同,可能会有相应调整。 |
[4] Jun Wada. Expert Opin Investig Drugs. Vaspin: a novel serpin with insulin-sensitizing effects
其他相关的Recombinant Proteins产品 |
---|
Recombinant Mouse Lumican (Mammalian, C-6His)
Lumican binds to laminin. It has positive regulation of transcription from RNA polymerase II promoter and transforming growth factor beta1 production. |
Recombinant Human Serpin A12 (E.coli, N-GST)
Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin is also a unique insulin sensitizing adipocytokine in obesity. |
Recombinant Human B2M Protein (Mammalian, C-6His)
β-2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family. B2M may adopt the fibrillar configuration of amyloid in certain pathologic states. |
Recombinant Mouse E-Selectin/CD62E Protein (HEK293)
E-selectin, also known as endothelial leukocyte adhesion molecule-1 (ELAM-1) and CD62E, is an inducible adhesion molecule that is expressed on the surfaces of stimulated vascular endothelial cells and is sometimes involved in cancer cell metastasis. |
Recombinant Human DPP4/CD26 (Mammalian, C-6His)
DPP4/CD26 is a signal-anchor for type II membrane protein that belongs to the peptidase S9B family. DPP4/CD26 acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. It’s binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. |
产品仅供科学研究或药证申报的用途使用,不为任何个人或者非科研性质的其他用途提供服务。
Copyright © 2010-2022 AbMole版权所有 沪ICP备16047849号 沪公网安备 31011502012228号