Immune Checkpoint Proteins Immune Checkpoint Proteins
| 目录号 | 产品名称 | 产品简介 |
|---|---|---|
M58710
|
Recombinant Human PD-L1 Protein (HEK293, C-Fc) | PD-L1 (also known as CD274, B7-H1) is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. By binding to PD1 on activated T-cells and B-cells, PD-L1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression. |
| M58674
|
Recombinant Human LAG-3 Protein (HEK293, C-hFc) | Lymphocyte activation gene 3 protein (LAG3) is a member of immunoglobulin (Ig) superfamily. LAG3 is selectively expressed in activated T and NK cells. LAG3 has a negative regulatory function in T cells and acts as as a new marker of T cell induced B cell activation. It can lead to increased antigen-specific T-cell responses in vivo. |
