找到约 5 条 “Sphingosine-1-phosphate” 相关结果 （用时 0.189 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
M7319
|
Sphingosine-1-phosphate | Sphingosine-1-phosphate | S1P Receptor |
| S1P | |||
| Sphingosine-1-phosphate (S1P) 是 S1P1-5 受体 (S1P1-5 receptors) 的激动剂和 GPR3、GPR6、GPR12 的配体。Sphingosine-1-phosphate 是细胞内的第二信使，动员 Ca2+ 作为 G 蛋白偶联受体的细胞外配体。 | |||
| M8431
|
CYM50358 | CYM50358 | S1P Receptor |
| CYM50358 is a potent, selective antagonist of the sphingosine-1-phosphate receptor 4 (S1P4). | |||
| M21034 | SKI-V | SKI-V | SPHK |
| SKI V is a noncompetitive and potent inhibitor of non-lipid sphingosine kinase with IC50 of 2 μM for GST-hSK. SKI-V also inhibits PI3K with IC50 of 6 μM for hPI3k. SKI-V decreases formation of the mitogenic second messenger sphingosine-1-phosphate (S1P) and induces apoptosis with antitumor activity. | |||
| M29857
|
CAY10444 | CAY10444 | LPL Receptor |
| BML-241 | |||
| CAY10444 (BML-241) 是一种 sphingosine-1-phosphate 3 (S1P3) 拮抗剂。CAY10444 在表达 S1P3 受体的 HeLa 细胞中抑制 37% S1P 诱导的 Ca2+ 增加。 | |||
| M39090 | Sphinganine 1-phosphate | Sphinganine 1-phosphate | Metabolite/Endogenous Metabolite |
| Sphinganine 1-phosphate (D-erythro-Dihydrosphingosine 1-phosphate) 是一种极性鞘脂代谢物，可调节细胞迁移、细胞分化等众多生理过程。 | |||
