找到约 1 条 “Quisinostat (JNJ-26481585) 2HCl” 相关结果 （用时 0.22 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
| M20389 | Quisinostat (JNJ-26481585) 2HCl | Quisinostat (JNJ-26481585) 2HCl | HDAC |
| Quisinostat (JNJ-26481585) 2HCl is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11 greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7. Phase 2. | |||