找到约 6 条 “PHD-IN-2” 相关结果 （用时 0.13 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
| M42440 | PHD-IN-2 | PHD-IN-2 | HIF |
| PHD-IN-2 是一种 PHD 拮抗剂 (IC50: <5 nM)。 | |||
M25395
|
GSK1379725A | GSK1379725A | Epigenetic Reader Domain |
| AU1; AU-1 | |||
| GSK1379725A（AU1）是首个选择性的BPTF（Bromodomain PHD Finger Transcription Factor）配体，Kd值为2.8uM，对Brd4无结合活性。 | |||
| M8467 | OF-1 | OF-1 | Others |
| OF-1 is a chemical probe for the bromodomains of the BRPF (BRomodomain and PHD Finger containing) family of scaffolding proteins (BRPF1, BRPF2, BRPF3) that assemble histone acetyltransferase (HAT) complexes of the MYST family members MOZ and MORF. | |||
| M20749 | TP0463518 | TP0463518 | HIF |
| TP0463518 is a potent hypoxia-inducible factor prolyl hydroxylases (PHDs) inhibitor with Ki of 5.3 nM for human PHD2. TP0463518 inhibits human PHD1, human PHD3 and monkey PHD2 with IC50 of 18 nM, 63 nM and 22 nM, respectively. | |||
| M42436 | PHD2-IN-1 | PHD2-IN-1 | HIF |
| PHD2-IN-1 是一种强效的、具有口服活性的 HIF-脯氨酰羟化酶2 (PHD2) 抑制剂，IC50 为 22.53 nM，可用于贫血病研究。 | |||
| M42439 | PHD-IN-1 | PHD-IN-1 | HIF |
| PHD-IN-1 是一种有效的 PHD2 抑制剂，IC50 值 ≤5 nM。 | |||
