找到约 2 条 “NSC-87877” 相关结果 （用时 0.281 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
M7059
|
NSC-87877 | NSC-87877 | Phosphatase |
| NSC87877 | |||
| NSC-87877 是一种有效的Shp2 和Shp1 蛋白质酪氨酸磷酸酶抑制剂，IC50 值分别为0.318 μM 和0.355 μM。NSC-87877还抑制双特异性磷酸酶26 (DUSP26)。 | |||
| M20614 | NSC-87877 disodium salt | NSC-87877 disodium salt | Phosphatase |
| NSC-87877 disodium is a cell-permeable inhibitor of both SHP-1 and SHP-2 with IC50 values of 355 and 318 nM respectively. NSC-87877 disodium salt also inhibits EGF-induced Erk1/2 activation in HEK293 cells and significantly reduces MDA-MB-468 cell viability/proliferation. | |||
