HDAC8-IN-4 - 搜索结果 | AbMole中文官网

找到约 4 条 “HDAC8-IN-4” 相关结果（用时 0.257 秒）

目录号	产品名称	中文名称	靶点
M41502	HDAC8-IN-4	HDAC8-IN-4	HDAC
	HDAC8-IN-4 是 HDAC8 的选择性抑制剂。
M8624	HPB	HPB	Others
	HPB is a cell-permeable, non-cytotoxic N-hydroxybenzamide derivative that acts as a HDAC6-selective deacetylase inhibitor (IC₅₀ = 31/376/677/842/1133 nM against HDAC6/8/10/1/7, >2 μM against HDAC2/3/4/11/9/5).
M20644	TH34	TH34	HDAC
	TH34 is a HDAC inhibitor that shows pronounced selectivity for HDACs 6, 8 and 10 over HDACs 1, 2 and 3. In a NanoBRET assay, TH34 strongly binds HDAC6, 8 and 10 with low-micromolar IC50 concentrations (HDAC6: 4.6 µM, HDAC8: 1.9 µM, HDAC10: 7.7 µM).
M40605	Snail/HDAC-IN-1	Snail/HDAC-IN-1	HDAC
	Snail/HDAC-IN-1是一种有效的 Snail/HDAC 双靶点抑制剂，对 HDAC1 有较强的抑制活性，其IC50值为0.405 μM，对 Snail 有较强的抑制作用，Kd 为 0.18 μM。此外，Snail/HDAC-IN-1 也能增加 HCT-116 细胞中的组蛋白 H4 乙酰化，同时降低 Snail 蛋白表达，从而诱导细胞凋亡 (apoptosis)。