找到约 31 条 “Dim16” 相关结果 (用时 0.224 秒)

目录号 产品名称 中文名称 靶点
M11756 ChemBridge-5169181 ChemBridge化合物-5169181 Screening Compounds and Building Blocks
6,9-dimethyl-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide (5169181)
ChemBridge特有类药化合物/先导化合物-5169181,由AbMole(奥默生物)独家提供。具体售价货期请咨询AbMole(奥默生物)。运费额外计算。
M11870 ChemBridge-5231609 ChemBridge化合物-5231609 Screening Compounds and Building Blocks
2-[(3-cyano-5-ethyl-4,6-dimethyl-2-pyridinyl)thio]acetamide (5231609)
ChemBridge特有类药化合物/先导化合物-5231609,由AbMole(奥默生物)独家提供。具体售价货期请咨询AbMole(奥默生物)。运费额外计算。
M12601 ChemBridge-6161287 ChemBridge化合物-6161287 Screening Compounds and Building Blocks
6,8-dimethyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid (6161287)
ChemBridge特有类药化合物/先导化合物-6161287,由AbMole(奥默生物)独家提供。具体售价货期请咨询AbMole(奥默生物)。运费额外计算。
M13058 ChemBridge-7911696 ChemBridge化合物-7911696 Screening Compounds and Building Blocks
N-(3-acetylphenyl)-3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide (7911696)
ChemBridge特有类药化合物/先导化合物-7911696,由AbMole(奥默生物)独家提供。具体售价货期请咨询AbMole(奥默生物)。运费额外计算。
M13194 ChemBridge-9053163 ChemBridge化合物-9053163 Screening Compounds and Building Blocks
N-(2,5-dimethylphenyl)-2-[4-(3-phenyl-2-propen-1-yl)-1-piperazinyl]acetamide (9053163)
ChemBridge特有类药化合物/先导化合物-9053163,由AbMole(奥默生物)独家提供。具体售价货期请咨询AbMole(奥默生物)。运费额外计算。
M13249 ChemBridge-16707928 ChemBridge化合物-16707928 Screening Compounds and Building Blocks
6,8-dimethyl-3-(4-phenyl-1H-imidazol-5-yl)quinolin-2(1H)-one (16707928)
ChemBridge特有类药化合物/先导化合物-16707928,由AbMole(奥默生物)独家提供。具体售价货期请咨询AbMole(奥默生物)。运费额外计算。
M42609 Dim16 Dim16 Serine/Threonine Protease
Dim16 是一种双重 PCSK9/HMG-CoAR 抑制剂,对 PCSK9 的 IC50 值为 19 nM。
M45473 ChemBridge-5161613 ChemBridge化合物-5161613 Screening Compounds and Building Blocks
2-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1,3-dioxo-5-isoindolinecarboxylic acid (5161613)
ChemBridge特有类药化合物/先导化合物-5161613,由AbMole(奥默生物)独家提供。具体售价货期请咨询AbMole(奥默生物)。运费额外计算。
M45476 ChemBridge-5169001 ChemBridge化合物-5169001 Screening Compounds and Building Blocks
ethyl 4-[(dimethylamino)methyl]-5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate (5169001)
ChemBridge特有类药化合物/先导化合物-5169001,由AbMole(奥默生物)独家提供。具体售价货期请咨询AbMole(奥默生物)。运费额外计算。
M45823 ChemBridge-6129816 ChemBridge化合物-6129816 Screening Compounds and Building Blocks
2-(4-chlorophenyl)-N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)acetamide (6129816)
ChemBridge特有类药化合物/先导化合物-6129816,由AbMole(奥默生物)独家提供。具体售价货期请咨询AbMole(奥默生物)。运费额外计算。
M45909 ChemBridge-6433074 ChemBridge化合物-6433074 Screening Compounds and Building Blocks
17-benzyl-1,8-dimethyl-17-azapentacyclo[6.6.5.0~2,7~.0~9,14~.0~15,19~]nonadeca-2,4,6,9,11,13-hexaene-16,18-dione (6433074)
ChemBridge特有类药化合物/先导化合物-6433074,由AbMole(奥默生物)独家提供。具体售价货期请咨询AbMole(奥默生物)。运费额外计算。
M46144 ChemBridge-7416846 ChemBridge化合物-7416846 Screening Compounds and Building Blocks
3-(3,4-dimethoxyphenyl)-1-(5-fluoro-3-methyl-1-benzofuran-2-yl)-2-propen-1-one (7416846)
ChemBridge特有类药化合物/先导化合物-7416846,由AbMole(奥默生物)独家提供。具体售价货期请咨询AbMole(奥默生物)。运费额外计算。
M46342 ChemBridge-7841605 ChemBridge化合物-7841605 Screening Compounds and Building Blocks
N-(4-sec-butylphenyl)-N'-(4-chloro-2,5-dimethoxyphenyl)thiourea (7841605)
ChemBridge特有类药化合物/先导化合物-7841605,由AbMole(奥默生物)独家提供。具体售价货期请咨询AbMole(奥默生物)。运费额外计算。
M46357 ChemBridge-7871673 ChemBridge化合物-7871673 Screening Compounds and Building Blocks
(3,4-dimethoxybenzyl)(2-thienylmethyl)amine hydrochloride (7871673)
ChemBridge特有类药化合物/先导化合物-7871673,由AbMole(奥默生物)独家提供。具体售价货期请咨询AbMole(奥默生物)。运费额外计算。
M46412 ChemBridge-7922169 ChemBridge化合物-7922169 Screening Compounds and Building Blocks
N-{4-[(ethylamino)sulfonyl]phenyl}-7,8-dimethyl-2-(2-pyridinyl)-4-quinolinecarboxamide (7922169)
ChemBridge特有类药化合物/先导化合物-7922169,由AbMole(奥默生物)独家提供。具体售价货期请咨询AbMole(奥默生物)。运费额外计算。
M46621 ChemBridge-8831416 ChemBridge化合物-8831416 Screening Compounds and Building Blocks
N-1-adamantyl-N'-(3,4-dimethoxyphenyl)thiourea (8831416)
ChemBridge特有类药化合物/先导化合物-8831416,由AbMole(奥默生物)独家提供。具体售价货期请咨询AbMole(奥默生物)。运费额外计算。
M46658 ChemBridge-8891646 ChemBridge化合物-8891646 Screening Compounds and Building Blocks
6,8-dichloro-N-(2,4-dimethylphenyl)-3-nitrodibenzo[b,f]oxepine-1-carboxamide (8891646)
ChemBridge特有类药化合物/先导化合物-8891646,由AbMole(奥默生物)独家提供。具体售价货期请咨询AbMole(奥默生物)。运费额外计算。
M46781 ChemBridge-9021686 ChemBridge化合物-9021686 Screening Compounds and Building Blocks
N-{4-[(2,6-dimethyl-4-morpholinyl)sulfonyl]phenyl}-2-furamide (9021686)
ChemBridge特有类药化合物/先导化合物-9021686,由AbMole(奥默生物)独家提供。具体售价货期请咨询AbMole(奥默生物)。运费额外计算。
M46828 ChemBridge-9061695 ChemBridge化合物-9061695 Screening Compounds and Building Blocks
1-[(5-chloro-2-methoxy-4-methylphenyl)sulfonyl]-3,5-dimethyl-1H-pyrazole (9061695)
ChemBridge特有类药化合物/先导化合物-9061695,由AbMole(奥默生物)独家提供。具体售价货期请咨询AbMole(奥默生物)。运费额外计算。
M46951 ChemBridge-9131690 ChemBridge化合物-9131690 Screening Compounds and Building Blocks
2,3-dimethyl-5-oxo-N-propyl-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide (9131690)
ChemBridge特有类药化合物/先导化合物-9131690,由AbMole(奥默生物)独家提供。具体售价货期请咨询AbMole(奥默生物)。运费额外计算。
M47040 ChemBridge-9216123 ChemBridge化合物-9216123 Screening Compounds and Building Blocks
4-bromo-N-(2-hydroxyethyl)-2,5-dimethoxybenzenesulfonamide (9216123)
ChemBridge特有类药化合物/先导化合物-9216123,由AbMole(奥默生物)独家提供。具体售价货期请咨询AbMole(奥默生物)。运费额外计算。
M47309 ChemBridge-12166660 ChemBridge化合物-12166660 Screening Compounds and Building Blocks
1'-(2-chloro-6-fluorobenzyl)-N,N-dimethyl-5,6-dihydrospiro[cyclopenta[d]pyrimidine-7,3'-piperidin]-2-amine (12166660)
ChemBridge特有类药化合物/先导化合物-12166660,由AbMole(奥默生物)独家提供。具体售价货期请咨询AbMole(奥默生物)。运费额外计算。
M47430 ChemBridge-16552103 ChemBridge化合物-16552103 Screening Compounds and Building Blocks
2-(dimethylamino)-N-(4-methyl-3-{[(2,3,6-trifluorophenyl)acetyl]amino}phenyl)acetamide (16552103)
ChemBridge特有类药化合物/先导化合物-16552103,由AbMole(奥默生物)独家提供。具体售价货期请咨询AbMole(奥默生物)。运费额外计算。
M47433 ChemBridge-16717375 ChemBridge化合物-16717375 Screening Compounds and Building Blocks
2-[(dimethylamino)methyl]-N-(7-methoxy-2,1,3-benzoxadiazol-4-yl)-1,3-thiazole-4-carboxamide (16717375)
ChemBridge特有类药化合物/先导化合物-16717375,由AbMole(奥默生物)独家提供。具体售价货期请咨询AbMole(奥默生物)。运费额外计算。
M47434 ChemBridge-16739360 ChemBridge化合物-16739360 Screening Compounds and Building Blocks
(3-chloro-4,5-dimethoxybenzyl)(8-methoxy-3,4-dihydro-2H-chromen-3-yl)amine (16739360)
ChemBridge特有类药化合物/先导化合物-16739360,由AbMole(奥默生物)独家提供。具体售价货期请咨询AbMole(奥默生物)。运费额外计算。
M47438 ChemBridge-16955124 ChemBridge化合物-16955124 Screening Compounds and Building Blocks
4-(2-amino-6-methoxypyrimidin-4-yl)-N-(2-hydroxy-1,1-dimethylethyl)benzamide (16955124)
ChemBridge特有类药化合物/先导化合物-16955124,由AbMole(奥默生物)独家提供。具体售价货期请咨询AbMole(奥默生物)。运费额外计算。
M47567 ChemBridge-21689185 ChemBridge化合物-21689185 Screening Compounds and Building Blocks
1-({6-[(diethylamino)methyl]pyrazolo[1,5-a]pyrimidin-3-yl}carbonyl)-N,N-dimethylpyrrolidin-3-amine (21689185)
ChemBridge特有类药化合物/先导化合物-21689185,由AbMole(奥默生物)独家提供。具体售价货期请咨询AbMole(奥默生物)。运费额外计算。
M47657 ChemBridge-25462167 ChemBridge化合物-25462167 Screening Compounds and Building Blocks
(1R*,5R*)-6-[(2-ethyl-4-methyl-1,3-thiazol-5-yl)carbonyl]-N,N-dimethyl-3,6-diazabicyclo[3.2.2]nonane-3-sulfonamide (25462167)
ChemBridge特有类药化合物/先导化合物-25462167,由AbMole(奥默生物)独家提供。具体售价货期请咨询AbMole(奥默生物)。运费额外计算。
M47674 ChemBridge-26162639 ChemBridge化合物-26162639 Screening Compounds and Building Blocks
N-cyclopentyl-6-(dimethylamino)-N-[(5-methyl-2-thienyl)methyl]nicotinamide (26162639)
ChemBridge特有类药化合物/先导化合物-26162639,由AbMole(奥默生物)独家提供。具体售价货期请咨询AbMole(奥默生物)。运费额外计算。
M47803 ChemBridge-31090716 ChemBridge化合物-31090716 Screening Compounds and Building Blocks
N-(5,6-dimethyl-4-phenyl-2-pyridinyl)-4-(1,3-oxazol-5-yl)benzamide (31090716)
ChemBridge特有类药化合物/先导化合物-31090716,由AbMole(奥默生物)独家提供。具体售价货期请咨询AbMole(奥默生物)。运费额外计算。
M58101 Recombinant Human EGFR Protein (CHO, C-His) 重组人EGFR 蛋白 (CHO, C-His) Cytokines and Growth Factors
ERBB; ERBB1; HER1; Epidermal Growth Factor Receptor
EGFR, also known as ERBB, ERBB1 and HER1, is a type I transmembrane protein belonging to the tyrosine protein kinase family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. EGFR also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling.








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