找到约 3 条 “Caf1-IN-1” 相关结果 （用时 0.11 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
| M43422 | DCAF1 binder 1 | DCAF1 binder 1 | Ligand for E3 Ligase |
| DCAF1 binder 1 对 CRL4 DCAF1 E3 连接酶复合物具有选择性。 | |||
M58164
|
Caf1-IN-1 | Caf1-IN-1 | DNA/RNA Synthesis |
| Compound 8j | |||
| Caf1-IN-1 是 核糖核酸酶 Caf1 的抑制剂，IC50 为 0.59 µM。Caf1-IN-1 还是 多(A) 特异性核糖核酸酶 (PARN) 的弱抑制剂，IC50 为 23.9 µM。 | |||
| M20775 | SEC inhibitor KL-1 | SEC inhibitor KL-1 | Others |
| KL-1 | |||
| SEC inhibitor KL-1 (KL-1) is a potent and selective inhibitor of super elongation complex (SEC) that disrupts the interaction between the SEC scaffolding protein AFF4 and P-TEFb, resulting in impaired release of Pol II from promoter-proximal pause sites and a reduced average rate of processive transcription elongation. KL-1 exhibits an dose-dependent inhibitory effect on AFF4-CCNT1 interaction with Ki of 3.48 μM. | |||
