找到约 2 条 “BMPR2-IN-1” 相关结果 （用时 0.35 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
| M43580 | BMPR2-IN-1 | BMPR2-IN-1 | TGF-β Receptor |
| MPR2-IN-1 是一种 BMPR2 抑制剂，IC50 为 506 nM，K D 为 83.5 nM。 | |||
M55622
|
Recombinant Human BMPRIA/ALK-3/CD292 Protein (HEK293, C-His) | 重组人BMPRIA/ALK-3/CD292 蛋白 (HEK293, C-His) | Cytokines and Growth Factors |
| Bone Morphogenetic Protein Receptor type IA; Activin receptor-Like Kinase 3; ACVRLK3 | |||
| BMPR1A/ALK-3/CD292 protein is expressed in the epithelium during branching morphogenesis. It is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the transforming growth factor beta (TGF-β) superfamily. BMPR1A/ALK-3 plays an essential role in the formation of embryonic ventral abdominal wall, and abrogation of BMP signaling activity due to gene mutations in its signaling components could be one of the underlying causes of omphalocele at birth. The type IA BMP receptor, ALK-3 was specifically required at mid-gestation for normal development of the trabeculae, compact myocardium, interventricular septum, and endocardial cushion. | |||
