找到约 1 条 “BI-671800” 相关结果 (用时 0.18 秒)
目录号 | 产品名称 | 中文名称 | 靶点 |
---|---|---|---|
M20981 | BI-671800 | BI-671800 | Prostaglandin Receptor |
AP-761, Cmpd A | |||
BI-671800 (AP-761, Cmpd A) is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2) with IC50 of 4.5 nM and 3.7 nM for PGD2 binding to human CRTH2 and murine CRTH2, respectively. BI-671800 is associated with a small improvement in FEV1 in symptomatic controller-naïve asthma patients, and in patients on ICS. |
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