找到约 37 条 “7BIO” 相关结果 （用时 0.107 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
M2456
|
Biotin | D-生物素 | Others |
| Vitamin B7; Vitamin H; D-Biotin | |||
| Biotin (Vitamin B7，D-生物素)是一种水溶性的维生素B，对于细胞生长，脂肪酸生成以及脂肪和氨基酸代谢是必需的。它在三羧酸循环过程中发挥作用。Biotin也是一种羧化酶辅酶，参与脂肪酸，异亮氨酸和缬氨酸的合成以及糖异生过程。此外， biotin广泛用于生物技术产业标记蛋白质进行生化研究。 | |||
M2790
|
K252a | K252a | PKC |
| SF 2370; Antibiotic K-252a | |||
| K252a 是BDNF 受体 TrkB 的抑制剂。K-252a 对 PKC、PKA、II型钙调素依赖性激酶和磷酸化酶激酶的 IC50 值分别为470 nM、140 nM、270 nM和1.7 nM。K-252a 抑制 NGF 受体 gp140trk 的酪氨酸蛋白激酶 (TRK) 活性，IC50 为 3 nM。 | |||
| M9780
|
Nigericin | Nigericin | Potassium Channel |
| Antibiotic K178, Antibiotic X464 | |||
| Nigericin is an antibiotic derived from Streptomyces hygroscopicus, it acts as an H+, K+, Pb2+ ionophore. | |||
| M11236
|
Lasalocid sodium | 拉沙洛西钠；拉沙里菌素钠；那塞罗钠 | Antibiotic |
| Lasalocid-A sodium; Ionophore X-537A sodium; Antibiotic X-537A | |||
| Lasalocid sodium (Lasalocid-A sodium) 是一个抗菌剂。 | |||
| M11833 | ChemBridge-5214872 | ChemBridge化合物-5214872 | Screening Compounds and Building Blocks |
| 6-bromo-5-methyl-1H-indole-2,3-dione 3-[(6-bromo-5-methyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazone] (5214872) | |||
| ChemBridge特有类药化合物/先导化合物-5214872，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M11856 | ChemBridge-5225755 | ChemBridge化合物-5225755 | Screening Compounds and Building Blocks |
| 5,7-dibromo-1H-indole-2,3-dione 3-oxime (5225755) | |||
| ChemBridge特有类药化合物/先导化合物-5225755，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M12269 | ChemBridge-5676368 | ChemBridge化合物-5676368 | Screening Compounds and Building Blocks |
| 4-chloro-7-methyl-1H-indole-2,3-dione 3-oxime (5676368) | |||
| ChemBridge特有类药化合物/先导化合物-5676368，由AbMole（奥默生物）独家提供。具体售价货期请咨询AbMole（奥默生物）。运费额外计算。 | |||
| M13469 | Lasalocid | Lasalocid | Antibiotic |
| Lasalocid-A; Ionophore X-537A; Antibiotic X-537A | |||
| Lasalocid (Lasalocid-A; Ionophore X-537A; Antibiotic X-537A) 是一种抗菌剂和抗球虫药, 用在饲料添加剂中。 | |||
| M17973 | Quercetin-3-O-beta-D-glucose-7-O-beta-D-gentiobioside | 槲皮素-3-O-β-D-葡萄糖-7-O-β-D-龙胆双糖苷 | Others |
| Quercetin-3-O-β-D-glucose-7-O-β-D-gentiobiosiden 是来自于Quercetin 的一种黄酮。 | |||
| M17977 | Isorhamnetin 3-O-β-D-glucose-7-O-β-D-gentiobioside | 异鼠李素-3-O-β-D-葡萄糖-7-O-β-D-龙胆双糖苷 | Others |
| Isorhamnetin 3-O-β-D-glucose-7-O-β-D-gentiobioside 是一种生物活性成分，存在于 Lepidium apetalum Willd 的种子中。 | |||
| M18005 | Apigenin 7-O-(2G-rhamnosyl)gentiobioside | 芹菜素-7-0-（2G-鼠李糖）龙胆糖苷 | Others |
| Apigenin-7-O-(2G-rhamnosyl)gentiobioside 是从Lonicera gracilipes var. glandulosa 中提取的到的一种黄酮类苷化合物。 | |||
| M18184 | Chrysin 7-O-β-gentiobioside | 白杨素-7-O-龙胆二糖苷 | Others |
| Chrysin 7-O-beta-gentiobioside (Chrysin 7-O-β-gentiobioside) 是Chrysin 的糖基化产物。 | |||
| M39779 | 17α-Thevebioside | 17α-Thevebioside | Others |
| 17α-Thevebioside是从 Cerbera manghas 和 C. odollam 的风干叶中分离得到的化合物。 | |||
| M39943 | 7-O-Methylbiochanin A | 7-O-Methylbiochanin A | Others |
| 7-O-Methylbiochanin A (4',7-Dimethoxy-5-hydroxyisoflavone) 是一种从 Lotus polyphyllos 的根中分离出来异黄酮衍生物。 | |||
| M44476 | Naringenin 7-O-gentiobioside | 柚皮素-7-O-龙胆二糖苷 | Others |
| 柚皮素-7-O-龙胆二糖苷 | |||
| M44585 | Tectorigenin 7-O-gentiobioside | 鸢尾黄素 7-O-beta-龙胆双糖苷 | Others |
| 鸢尾黄素 7-O-beta-龙胆双糖苷 | |||
| M49510 | 7BIO | 7BIO | CDK |
| 7BIO (7-Bromoindirubin-3-Oxime) 是靛玉红的衍生物。 | |||
| M51396 | (Lys(Me)327)-Histone H3 (21-44)-Gly-Lys(biotinyl) | (Lys(Me)327)-Histone H3 (21-44)-Gly-Lys(biotinyl) | Others |
| (Lys(Me)327)-Histone H3 (21-44)-Gly-Lys(biotinyl) 是一种多肽，能够由多肽筛选发现。 | |||
| M51413 | (Lys(Me, Me)27)-Histone H3 (21-44)-Gly-Lys(Biotinyl) | (Lys(Me, Me)27)-Histone H3 (21-44)-Gly-Lys(Biotinyl) | Others |
| (Lys(Me,Me)27)-Histone H3 (21-44)-Gly-Lys(Biotinyl) 是一种多肽，能够由多肽筛选发现。 | |||
| M53161 | GLP-1 (7-36)-Lys(biotinyl) amide (human, bovine, guinea pig, mouse, rat) | GLP-1 (7-36)-Lys(biotinyl) amide (human, bovine, guinea pig, mouse, rat) | GLP Receptor |
| GLP-1 (7-36)-Lys(biotinyl) amide 是生物素化的 GLP-1 片段，对应于 GLP-1 的 7-36 序列。 | |||
| M4941
|
Lomefloxacin | 洛美沙星 | Antibiotic |
| Maxaquin,SC47111A | |||
| Lomefloxacin (SC47111A) 是一种广谱喹诺酮类 (antibiotic)抗生素，具有抗菌活性。 | |||
| M6716 | ER 819762 | ER 819762 | Others |
| ER 819762 is a potent EP 4 receptor antagonist; orally bioavailable. | |||
| M7091 | Org 48762-0 | Org 48762-0 | Others |
| Org 48762-0 is a selective p38α/β inhibitor; orally bioavailable. | |||
| M7413
|
TMI 1 | TMI 1 | MMP |
| TMI 1 is a adam 17 (TACE) and MMP inhibitor; orally bioavailable. | |||
| M8562 | SID 3712249 | SID 3712249 | Others |
| MiR-544 Inhibitor 1 | |||
| SID 3712249 (MiR-544 Inhibitor 1) is an inhibitor of the biogenesis of microRNA-544 (miR-544). | |||
| M8757 | TASIN-1 hydrochloride | TASIN-1 hydrochloride | Others |
| TASIN-1 (Truncated APC Selective INhibitor-1) targets EBP- (Emopamil-binding protein; D8-D7 sterol isomerase) dependent cholesterol biosynthesis and selectively induces cellular cholesterol depletion and apoptotic death in human colorectal cancer (CRC). | |||
| M19869
|
Lefamulin acetate (Xenleta) | Lefamulin acetate (Xenleta) | Antibiotic |
| BC-3781 acetate | |||
| Lefamulin acetate (Xenleta, BC-3781 acetate) is a pleuromutilin antibiotic for community-acquired bacterial pneumonia (CABP) treatment. Lefamulin acetate inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome, thus preventing the binding of transfer RNA for peptide transfer. | |||
| M20652 | JNJ-38877618 | JNJ-38877618 | c-Met |
| JNJ-38877618 (OMO-1) is a potent, highly selective, orally bioavailable MET kinase inhibitor with binding affinity (Kd) of 1.4 nM and enzyme inhibitory activity against wt and M1268T mutant MET (2 and 3 nM IC50). | |||
| M20789 | Neticonazole | Neticonazole | Others |
| SS717 | |||
| Neticonazole (SS717) is a selecvie inhibitor of exosome biogenesis and secretion. Neticonazole exhibits Neticonazole antifungal and antitumor activity. | |||
| M20822
|
PF-4136309 | PF-4136309 | CCR |
| INCB8761, PF-04136309 | |||
| PF-4136309 (INCB8761, PF-04136309) is a potent, selective, and orally bioavailable CCR2 antagonist with an IC50 of 5.2 nM for human CCR2. | |||
| M20884 | RG3039 | RG3039 | DNA/RNA Synthesis |
| PF-06687859, PF 6687859, Quinazoline 495 | |||
| RG3039 (PF-06687859, PF 6687859, Quinazoline 495) is an orally bioavailable and brain-penetrant inhibitor of the mRNA decapping enzyme DcpS with IC50 of 4.2 nM and IC90 of 40 nM, respectively. | |||
| M25536
|
Recombinant Human CXCL13/BCA-1 (E. coli) | 重组人CXCL13/BCA-1蛋白 (E. coli) | Recombinant Proteins |
| CXC chemokine BLC; Small-inducible cytokine B13 | |||
| CXCL13, also known as B-lymphocyte chemoattractant (BLC), is a CXC chemokine that is constitutively expressed in secondary lymphoid organs. Recombinant human CXCL13 is a single non-glycosylated polypeptide chain containing 87 amino acids and mature human BCA-1 shares 64 % amino acid sequence similarity with the murine protein and 23–34 % amino acid sequence identity with other known CXC chemokines. Determined by a chemotaxis bioassay using human B cells, the biological activity is in a concentration range of 1.0-10 ng/ml. | |||
| M27732 | Lefamulin | Lefamulin | Antibiotic |
| BC-3781 | |||
| Lefamulin (BC-3781) 是一种具有口服活性的抗生素 (antibiotic)。Lefamulin 通过与 50S 细菌核糖体的肽基转移酶 peptidyl transferase 中心结合来抑制蛋白质合成。Lefamulin 具有抗炎活性。Lefamulin 可用于研究细菌感染，如细菌性肺炎。 | |||
| M28184 | Debio 0617B | Debio 0617B | STAT |
| Debio 0617B 是一种多激酶抑制剂，可减少原代人 AML CD34+ 干/祖细胞的维持和自我更新。Debio 0617B 靶向 STAT3/STAT5 信号上游关键激酶，如 JAK、SRC、ABL 和 III/V 类受体酪氨酸激酶。Debio 0617B 在 STAT3 驱动的实体瘤中具有功效。 | |||
| M29098 | APS-2-79 | APS-2-79 | MEK |
| APS-2-79 是一种 KSR 依赖性的 MEK 拮抗剂。APS-2-79 与 ATPbiotin 竞争性地结合到 KSR2-MEK1 复合物内的 KSR2，IC50 为 120 nM。APS-2-79 与 KSR 结合可将 KSR 固定在一个非活性的状态，使其无法再结合 RAF 和激活 MEK，从而阻断了 Ras-MAPK 信号通路。 | |||
| M54737
|
Recombinant Human GAD67 Protein (Baculovirus-Insect, C-His) | 重组人GAD67 蛋白 (Baculovirus-Insect, C-His) | Recombinant Proteins |
| GAD1; Glutamate decarboxylase 1 | |||
| GAD67 (GAD1) is a member of thegroup II decarboxylase family. GAD67 is expressed in benign and malignant prostatic tissue and may serve as a highly prostate-specific tissue biomarker. | |||
| M54868 | BIO-7488 | BIO-7488 | IRAK |
| BIO7488 | |||
| BIO-7488 是一种具有口服活性的、强效的、选择性和中枢神经系统渗透性 IRAK4 抑制剂，BIO-7488 具有优异的 ADME 特性，可以用于神经炎症的研究。BIO-7488 对 IRAK4和 hERG 的 IC50 值分别为 0.6 nM 和 > 30 μM。 | |||
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