找到约 1 条 “63512-50-5” 相关结果 (用时 0.393 秒)
目录号 | 产品名称 | 中文名称 | 靶点 |
---|---|---|---|
M20864 | L-2-Hydroxyglutaric acid disodium | L-2-Hydroxyglutaric acid disodium | Histone demethylase |
(S)-2-Hydroxyglutaric acid disodium, L-2-Hydroxyglutarate disodium, LGA, L-2HG | |||
L-2-Hydroxyglutaric acid disodium ((S)-2-Hydroxyglutaric acid disodium, L-2-Hydroxyglutarate disodium, LGA, L-2HG) is an epigenetic modifier and a putative oncometabolite in kidney cancer that inhibits histone demethylases and hence promotes histone methylation. L-2-Hydroxyglutaric acid disodium is also an inhibitor of mitochondrial creatine kinase (Mi-CK) with Km and Ki of 2.52 mM and 11.13 mM, respectively. |