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Recombinant Mouse IL-23 (Mammalian) 重组小鼠IL-23蛋白 (Mammalian)

目录号 M21679 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


重组白介素 23 (IL-23) 是一种异二聚体细胞因子,由两个二硫键连接的亚基组成,一个是 IL-23 独有的 p19 亚基,一个是与 IL-12 共有的 p40 亚基。IL-23 诱导人 T 细胞增殖和 IFN-γ 产生。通过在 293F 人胚胎肾细胞中诱导 STAT 报告基因活性的能力测得的 ED50 为 501.08 ng/ml。

Recombinant Mouse IL-23 (Mammalian)结构式

别名:Interleukin-23

规格 价格 库存状态
10ug ¥ 2800 中国库存现货
50ug ¥ 7800 中国库存现货
其他规格数量报价?

质量标准及产品资料
  • 纯度: >95%, Endotoxin < 1 EU/μg
  • COA
  • MSDS
生物活性

重组白介素 23 (IL-23) 是一种异二聚体细胞因子,由两个二硫键连接的亚基组成,一个是 IL-23 独有的 p19 亚基,一个是与 IL-12 共有的 p40 亚基。IL-23 诱导人 T 细胞增殖和 IFN-γ 产生。

通过在 293F 人胚胎肾细胞中诱导 STAT 报告基因活性的能力测得的 ED50 为 501.08 ng/ml。

化学性质
溶解性(25°C) Reconstitute the lyophilized powder in distilled water to a concentration of 100μg/ml
储存条件 Stored at ≤ -20°C, stable for one year after receipt
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
参考文献

[1] Jiong Zhang, et al. Int Immunopharmacol. HMGB1-TLR4-IL-23-IL-17A axis accelerates renal ischemia-reperfusion injury via the recruitment and migration of neutrophils

[2] Zhen Wang, et al. Autophagy. Autophagy-based unconventional secretion of HMGB1 by keratinocytes plays a pivotal role in psoriatic skin inflammation

[3] Nick Powell, et al. Gut. Interleukin-22 orchestrates a pathological endoplasmic reticulum stress response transcriptional programme in colonic epithelial cells

[4] Hsi-Hua Chi, et al. J Am Soc Nephrol. IL-36 Signaling Facilitates Activation of the NLRP3 Inflammasome and IL-23/IL-17 Axis in Renal Inflammation and Fibrosis

[5] Jacob S Lee, et al. Immunity. Interleukin-23-Independent IL-17 Production Regulates Intestinal Epithelial Permeability

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关键词:Recombinant Mouse IL-23 (Mammalian), Interleukin-23, Recombinant Mouse IL-23 (Mammalian)供应商, Recombinant Proteins抑制剂, 购买Recombinant Mouse IL-23 (Mammalian), Recombinant Mouse IL-23 (Mammalian)溶解度, Recombinant Mouse IL-23 (Mammalian)结构式








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