白细胞介素-1 α (IL-1α) 是一种非分泌型促炎细胞因子,产生于多种细胞,包括单核细胞、组织巨噬细胞、角质形成细胞和其他上皮细胞。使用鼠 D10S 细胞通过细胞增殖测定确定的ED 50小于 2.0 pg/ml,对应于 > 5.0 × 108 IU /mg 的比活性。
别名:Interleukin-1 alpha
白细胞介素-1 α (IL-1α) 是一种非分泌型促炎细胞因子,产生于多种细胞,包括单核细胞、组织巨噬细胞、角质形成细胞和其他上皮细胞。使用鼠 D10S 细胞通过细胞增殖测定确定的ED 50小于 2.0 pg/ml,对应于 > 5.0 × 108 IU /mg 的比活性。IL-1α具有广泛的活性,包括通过诱导 IL-2 释放刺激胸腺细胞增殖、B 细胞成熟和增殖、促有丝分裂 FGF 样活性以及刺激前列腺素和胶原酶从滑膜细胞释放的能力。
蛋白编号:# Q3U0Y6
表观分子量:17.9 kDa
剂型描述:从 PBS 中的 0.2 μm 过滤溶液冻干,pH 7.4。
溶解性(25°C) | Reconstitute the lyophilized powder in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. |
储存条件 |
Stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. |
运输方式 | 冰袋运输,根据产品的不同,可能会有相应调整。 |
[4] Kam Leung. 99mTc-Interleukin-18-binding protein-Fc-interlukin-1 receptor antagonist
[5] William P Arend. Cytokine Growth Factor Rev. The balance between IL-1 and IL-1Ra in disease
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