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Recombinant Mouse CCL21 Protein (E. coli) 重组小鼠CCL21蛋白 (E. coli)

目录号 M40811 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


C-C Motif Chemokine 21a (CCL21) is a small secreted cytokine that belongs to the intercrine beta (CC chemokine) family. Mouse CCL21 inhibits hemopoiesis and stimulates chemotaxis. It has chemotactic function in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils.

Recombinant Mouse CCL21 Protein (E. coli)结构式

别名:C-C Motif Chemokine 21a

规格 价格 库存状态
10ug ¥ 1710 中国库存现货
50ug ¥ 4185 中国库存现货
其他规格数量报价?

质量标准及产品资料
  • 纯度: >95%, Endotoxin < 1 EU/μg
  • COA
  • MSDS
生物活性

C-C Motif Chemokine 21a (CCL21) is a small secreted cytokine that belongs to the intercrine beta (CC chemokine) family. Mouse CCL21 inhibits hemopoiesis and stimulates chemotaxis. It has chemotactic function in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Mouse CCL21 shows preferential activity towards naive T-cells and may play a role in mediating homing of lymphocytes to secondary lymphoid organs.

Mouse CCL21 cDNA encodes a 133 amino acid residue protein with a 23 residue signal peptide that is cleaved to generate the 110 residue mature protein. Recombinant Mouse C-C Motif Chemokine 21a expressed the target gene encoding Ser24-Gly133.


Accession: P84444

Endotoxin < 1 EU/µg

Apparent Molecular Weight: 16 KDa, reducing conditions

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

化学性质
性状 Lyophilized powder
溶解性(25°C) Reconstitute the lyophilized powder in distilled water up to 100 μg/ml.
储存条件 Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
参考文献

[1] Qian Li et al. Brain Behav Immun. Drainage of senescent astrocytes from brain via meningeal lymphatic routes

[2] Ailar Sabbaghi et al. Virol J. A formulated poly (I:C)/CCL21 as an effective mucosal adjuvant for gamma-irradiated influenza vaccine

[3] Christoph Matti et al. J Leukoc Biol. CCL20 is a novel ligand for the scavenging atypical chemokine receptor 4

[4] Yan Wang et al. Sheng Wu Gong Cheng Xue Bao. [Protein expression profile of mast cells in response to recombinant VP1-VP4 of foot-and-mouth disease virus]

[5] Ping Chen et al. Cancer Sci. Low-dose paclitaxel improves the therapeutic efficacy of recombinant adenovirus encoding CCL21 chemokine against murine cancer

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