重组人TGFBR2蛋白 (Mammalian,C-Fc)由哺乳动物表达系统产生,编码Thr23-Asp159的目的基因在c端以Fc标签表达。Accession #:P37173。
别名:TGF-beta type II receptor
表达系统:Mammalian
纯度:还原SDS-PAGE测定大于95%
内毒素:经LAL测试,小于0.1 ng/ug (1 EU/ug)
存储及稳定性:冻干蛋白应在< -20°C保存,但在室温下可保存3周。重组蛋白溶液可在4-7℃下保存2-7天。重组样品的等分液在< -20°C下稳定3个月
生物活性:TGFBR2是一个单通型I型膜蛋白,包含一个蛋白激酶结构域。TGFBR2与另一受体蛋白以异源二聚体复合物的形式存在,并与tgf - β结合。通过tgf - β受体复合物触发的信号引发细胞的各种反应。其中一种反应是抑制细胞生长和分裂。基于这一作用,tgf - β受体2型有时被称为肿瘤抑制因子。TGFBR2的缺陷与马凡综合征、loys - deitz主动脉瘤综合征、Osler-Weber-Rendu综合征和各种类型肿瘤的发展有关。
储存条件 |
粉末型式 -20°C 3年;4°C 2年 溶于溶剂 -80°C 6个月;-20°C 1个月 |
运输方式 | 冰袋运输,根据产品的不同,可能会有相应调整。 |
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