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Recombinant Human RANK (Mammalian, C-6His) 重组人RANK蛋白 (Mammalian, C-6His)

目录号 M21714 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


重组人 RANK (C-6His)由哺乳动物表达系统产生,编码 Ile30-Pro212 的靶基因在 C 末端用 6His 标签表达。RANK 是 RANK 配体 (RANKL) 的受体,是调节破骨细胞分化和激活的 RANK/RANKL/OPG 信号通路的一部分。

Recombinant Human RANK (Mammalian, C-6His)结构式

别名:Receptor activator of NF-KB; CD265

规格 价格 库存状态
10ug ¥ 1800 中国库存现货
50ug ¥ 4230 中国库存现货
其他规格数量报价?

质量标准及产品资料
  • 纯度: >95%, Endotoxin < 1 EU/µg
  • COA
  • MSDS
生物活性

重组人 RANK (C-6His)由哺乳动物表达系统产生,编码 Ile30-Pro212 的靶基因在 C 末端用 6His 标签表达。RANK 是 RANK 配体 (RANKL) 的受体,是调节破骨细胞分化和激活的 RANK/RANKL/OPG 信号通路的一部分。

蛋白编号:Q9Y6Q6

表观分子量:25-30 KDa,还原条件

剂型描述:从 0.2 μm 过滤的 PBS 溶液中冻干,pH 7.4。

化学性质
溶解性(25°C) Dissolve the lyophilized protein in distilled water.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
储存条件 Stored at ≤ -20°C, stable for one year after receipt
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
参考文献

[1] A Llop-Guevara, et al. Ann Oncol. Association of RAD51 with homologous recombination deficiency (HRD) and clinical outcomes in untreated triple-negative breast cancer (TNBC): analysis of the GeparSixto randomized clinical trial

[2] Tomohiko Sano, et al. BMC Musculoskelet Disord. Expression of the RANK/RANKL/OPG system in the human intervertebral disc: implication for the pathogenesis of intervertebral disc degeneration

[3] Yilei Wei, et al. BMC Biotechnol. Heterologous expression, purification and function of the extracellular domain of human RANK

[4] I Silva, et al. Acta Reumatol Port. Rank/Rankl/opg: literature review

[5] Shiqian Zhang, et al. Arch Biochem Biophys. The affinity of human RANK binding to its ligand RANKL

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