Platelet factor 4 (PF-4/CXCL4) is expressed in megakaryocytes and stored in the α-granules of platelets. Recombinant human PF-4 can be proinflammatory and proatherogenic through multiple effects on monocytes, macrophages and endothelial cells.
别名：Platelet factor 4; SCYB4
Platelet factor 4 (PF-4/CXCL4) is expressed in megakaryocytes and stored in the α-granules of platelets. Recombinant human PF-4 can be proinflammatory and proatherogenic through multiple effects on monocytes, macrophages and endothelial cells.
Recombinant human PF-4 is a 7.8 kDa protein containing 70 amino acid residues, including the four highly conserved residues present in CXC chemokines.
Measured by the ability to inhibit human FGF-basic-dependent proliferation of NR6R 3T3 mouse fibroblast cells, the ED50 is < 10.0 ug/ml.
Accession: P02776
Apparent Molecular Weight: ~7.8 kDa
Endotoxin < 0.2 EU/μg
Lyophilized after extensive dialysis against PBS.
| 性状 | Lyophilized powder |
| 溶解性（25°C） | Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml. |
| 储存条件 | Stable for up to 6 months at ≤ -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. |
| 运输方式 | 冰袋运输，根据产品的不同，可能会有相应调整。 |
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