中性粒细胞活化肽2 (nap2)是在人血小板α颗粒中发现的血小板碱性蛋白(PBP)的羧基末端片段。nap2是CXC趋化因子的一个成员。蛋白构造：CXCL7 (Ala59-Asp128)，Accession # P02775。
别名：NAP-2/CXCL7 (E. coli)
种属：Human
表达系统: E. coli
纯度：SDS-PAGE分析> 97%，高效液相色谱分析> 97%
内毒素：LAL法测定蛋白质含量< 1 EU/μg
理论分子量：7.6 kDa
存储及稳定性：在接收后，该产品在-70°C或-20°C下保持稳定长达6个月。重组后，产品应在4°C下稳定1周或在-20°C下稳定3个月。避免反复的冻融循环。
生物活性：与标准相比完全具有生物活性。采用人外周血中性粒细胞的趋化性生物测定法测定的生物活性在1.0-10.0 ng/ml的浓度范围内。与其他包含CXC趋化因子的ELR结构域类似，如IL-8和GRO蛋白，NAP-2已被证明可以结合CXCR-2并趋化和激活中性粒细胞。虽然CTAP-III、β-TG和PBP代表了NAP-2的氨基末端延伸变体，并具有相同的CXC趋化因子结构域，但这些蛋白不表现出NAP-2活性。最近，研究表明，CTAP-III的额外氨基末端残基掩盖了暴露在NAP-2上的关键ELR受体结合域，这可能是NAP-2缺乏活性的原因。
| 溶解性（25°C） | Reconstitute the lyophilized powder in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/ml. |
| 储存条件 |
粉末型式 -20°C 3年；4°C 2年 溶于溶剂 -80°C 6个月；-20°C 1个月 |
| 运输方式 | 冰袋运输，根据产品的不同，可能会有相应调整。 |
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蛋白质研究