中性粒细胞活化肽2 (nap2)是在人血小板α颗粒中发现的血小板碱性蛋白(PBP)的羧基末端片段。nap2是CXC趋化因子的一个成员。蛋白构造：CXCL7 (Ala59-Asp128)，Accession # P02775。
别名：PPBP; B-TG1; Beta-TG; CTAP-III
种属：Human
表达系统：CHO
纯度：SDS-PAGE分析结果为98%
内毒素：凝胶凝血法测定蛋白质< 0.2 EU/μg
表观分子量：~ 9kda，还原条件下在SDS-PAGE上
存储及稳定性：在接收后，该产品在低于-70°C的环境下保持稳定长达6个月。重组后，产品应在4°C下稳定1周或在-20°C下稳定3个月。为了长期保存，建议添加载体蛋白(如0.1% BSA)。避免反复的冻融循环。
生物活性：人NAP-2/CXCL7对CHO-K1/Ga15/hCXCR1细胞(人Ga15和人CXCR1在CHO-K1细胞中稳定表达)Ca2+动员实验的EC50值小于0.1 μg/ml。NAP-2已被证明可以结合CXCR-2并吸引和激活中性粒细胞。虽然CTAP-III、β-TG和PBP代表了NAP-2的氨基末端延伸变体，并具有相同的CXC趋化因子结构域，但这些蛋白不表现出NAP-2活性。最近，研究表明，CTAP-III的额外氨基末端残基掩盖了暴露在NAP-2上的关键ELR受体结合域，这可能是NAP-2缺乏活性的原因。
| 溶解性（25°C） | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O or PBS up to 100 μg/ml. |
| 储存条件 |
粉末型式 -20°C 3年；4°C 2年 溶于溶剂 -80°C 6个月；-20°C 1个月 |
| 运输方式 | 冰袋运输，根据产品的不同，可能会有相应调整。 |
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蛋白质研究