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Recombinant Human NANS (E.coli, N-6His) 重组人NANS 蛋白 (E.coli, N-6His)

目录号 M21617 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


重组人NANS 是一种含有一个AFP类结构域的酶。NANS无处不在,并在西亚尔酸的生物合成途径中起作用。重组人NANS 由大肠杆菌表达系统生产,编码Met1-Ser359的目标基因在N端有一个6His标签。

Recombinant Human NANS (E.coli, N-6His)结构式

别名:N-Acetylneuraminate Synthase

规格 价格 库存状态
10ug ¥ 1665 中国库存现货
50ug ¥ 4095 中国库存现货
其他规格数量报价?

质量标准及产品资料
  • 纯度: >95%, Endotoxin < 1 EU/μg
  • COA
  • MSDS
生物活性

重组人NANS 是一种含有一个AFP类结构域的酶。NANS无处不在,并在西亚尔酸的生物合成途径中起作用。重组人NANS 由大肠杆菌表达系统生产,编码Met1-Ser359的目标基因在N端有一个6His标签。NANS产生N-乙酰神经氨酸(Neu5Ac)和2-酮-3-脱氧-D-甘油-D-半乳糖-壬酸(KDN)。它还可以使用6-磷酸N-乙酰氨基葡萄糖和6-磷酸甘露糖作为底物,分别生成磷酸化形式的Neu5Ac和KDN。

化学性质
溶解性(25°C) Water
Saline
PBS
储存条件 Store at ≤-70°C, stable for 6 months after receipt
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
参考文献

[1] S Feuerbaum, et al. Int J Med Microbiol. De-O-Acetylation of mucin-derived sialic acids by recombinant NanS-p esterases of Escherichia coli O157:H7 strain EDL933

[2] Nadja Saile, et al. Int J Med Microbiol. Growth advantage of Escherichia coli O104:H4 strains on 5-N-acetyl-9-O-acetyl neuraminic acid as a carbon source is dependent on heterogeneous phage-Borne nanS-p esterases

[3] Nadja Saile, et al. Appl Environ Microbiol. Escherichia coli O157:H7 Strain EDL933 Harbors Multiple Functional Prophage-Associated Genes Necessary for the Utilization of 5-N-Acetyl-9-O-Acetyl Neuraminic Acid as a Growth Substrate

[4] Chatchawal Phansopa, et al. Biochem J. Characterization of a sialate-O-acetylesterase (NanS) from the oral pathogen Tannerella forsythia that enhances sialic acid release by NanH, its cognate sialidase

[5] Michael John Aldape, et al. J Infect Dis. The leukemoid reaction in Clostridium sordellii infection: neuraminidase induction of promyelocytic cell proliferation

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