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Recombinant Human IL-17F (Mammalian, C-6His) 重组人IL-17F 蛋白(Mammalian, C-6His)

目录号 M21706 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


重组人白细胞介素 17F 由哺乳动物表达系统产生,编码 Arg31-Gln163 的靶基因在 C 端用 6His 标签表达。IL-17F 可以刺激其他几种细胞因子的产生,包括 IL-6、IL-8 和粒细胞集落刺激因子。

Recombinant Human IL-17F (Mammalian, C-6His)结构式

别名:Interleukin-17F human

规格 价格 库存状态
10ug ¥ 1890 中国库存现货
50ug ¥ 4815 中国库存现货
其他规格数量报价?

质量标准及产品资料
  • 纯度: >95%, Endotoxin < 1 EU/µg
  • COA
  • MSDS
生物活性

重组人白细胞介素 17F 由哺乳动物表达系统产生,编码 Arg31-Gln163 的靶基因在 C 端用 6His 标签表达。IL-17F 可以刺激其他几种细胞因子的产生,包括 IL-6、IL-8 和粒细胞集落刺激因子。IL-17F 在活化的而非静止的 CD4+ T 细胞和活化的单核细胞中表达。IL-17F 可以调节软骨基质更新并刺激 PBMC 和 T 细胞增殖。还发现 IL-17F 可抑制内皮细胞的血管生成并诱导内皮细胞产生 IL2、TGFB1/TGFB 和单核细胞趋化蛋白-1。

蛋白编号:AAH70124.1

表观分子量:19 KDa,还原条件

剂型描述:从 20mM PB、150mM NaCl、pH 7.4 的 0.2 μm 过滤溶液中冻干。

化学性质
溶解性(25°C) Dissolve the lyophilized protein in distilled water.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
储存条件 Stored at ≤ -20°C, stable for one year after receipt
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
参考文献

[1] Yuchao Chen, et al. Theranostics. Dihydroartemisinin ameliorates psoriatic skin inflammation and its relapse by diminishing CD8+ T-cell memory in wild-type and humanized mice

[2] Mittal Shah, et al. RMD Open. Dual neutralisation of IL-17F and IL-17A with bimekizumab blocks inflammation-driven osteogenic differentiation of human periosteal cells

[3] Jessica E Miller, et al. Front Immunol. IL-17A Modulates Peritoneal Macrophage Recruitment and M2 Polarization in Endometriosis

[4] Lei Wang, et al. Thorax. Targeting IL-17 attenuates hypoxia-induced pulmonary hypertension through downregulation of β-catenin

[5] Jacob S Lee, et al. Immunity. Interleukin-23-Independent IL-17 Production Regulates Intestinal Epithelial Permeability

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