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Recombinant Human IL-12 (HEK293) 重组人白介素12 (HEK293)

目录号 M9366 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


重组人白介素12(Recombinant Human IL-12)也称之为NK细胞刺激因子(NKSF)或者杀伤性淋巴细胞成熟因子(CLMF),它是一种多效细胞因子,最初是在人成熟的B淋巴样细胞系中鉴定的。

Recombinant Human IL-12 (HEK293)结构式

别名:Interleukin 12; IL12

规格 价格 库存状态
50ug ¥ 6400 中国库存现货
100ug ¥ 10500 中国库存现货
其他规格数量报价?

质量标准及产品资料
  • 纯度: >90%, Endotoxin < 0.1 EU/µg
  • COA
  • MSDS
生物活性

重组人IL-12蛋白是一种多效细胞因子,最初是在人成熟的 B 淋巴样细胞系中鉴定的。IL-12 主要由单核细胞和巨噬细胞产生,也可以由 B 细胞和 DC 产生。 IL-12 是一种异二聚体细胞 因子,由两个独立的基因 IL-12A(p35)和 IL-12B(p40)编码。IL-12 受体主要位于 T 细胞和 NK 细胞上.IL-12 可以刺激 Th1 和 NK 细胞生长,同时抑制 Th2 细胞反应。IL-12 可以通过促进 IFN- γ和 TNF-α的分泌以及抑制 IL-4 的产生增强 T 淋巴细胞和 NK 细胞的细胞毒性。

通过其诱导人自然杀伤性淋巴瘤 NK-92 细胞分泌干扰素γ的能力来测定,该效应的 ED50值为 ≤2 ng/mL。


蛋白序列:DNA 序列编码人 P29459-1(IL12A)& P29460-1(IL12B)异源二聚体

内毒素:<0.1 EU/μg

预测分子量为 65kD

化学性质
溶解性(25°C) Reconstitute the lyophilized powder in ddH2O or PBS. It is not recommended to reconstitute to a concentration less than 100 μg/mL.
储存条件 Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
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