重组人IGF-1(Recombinant Human IGF-1)是一种促有丝分裂多肽生长因子,能刺激各种细胞的增殖和存活,包括肌肉、骨骼和软骨组织。
别名:IGF1A; somatomedin C; MGF
重组人IGF-1(Recombinant Human IGF-1)是一种促有丝分裂多肽生长因子,能刺激各种细胞的增殖和存活,包括肌肉、骨骼和软骨组织。IGFS 主要由肝脏产生,属于胰岛素基因家族,也含有胰岛素和松弛素。IGF-Ⅰ和 IGF-Ⅱ信号通过酪氨酸激酶 I 型受体(IGF-IR),而 IGF-Ⅱ也能通过 IGF-Ⅱ/甘露糖-6-磷酸受体信号。成熟的 IGFS 是由含有 N 端和 C 端前体区的非活性前体蛋白经蛋白水解而产生的。
通过用MCF-7细胞进行细胞增殖测定,测得的ED50为≤10 ng/mL。
重组人IGF-1 包含 308 个氨基酸,预测分子量为 34.6 kD。
DNA 序列编码人 IGF-1(NP_001104754.1)表达带有 Fc 标签在 C 末端。
内毒素<0.1EU/μg
溶解性(25°C) | Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml. |
储存条件 | Stored at ≤-20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
运输方式 | 冰袋运输,根据产品的不同,可能会有相应调整。 |
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