IFN-γ is the major interferon produced by mitogenically or antigenically stimulated lymphocytes. Human Interferon gamma (hIFN-γ) is amacrophage‐activating factor. IFN-γ is also implicated in resistance to NK cell and CTL responses and in immune escape in a variety of cancers.
别名:IFN gamma; IFNG
IFN-γ is the major interferon produced by mitogenically or antigenically stimulated lymphocytes. Human Interferon gamma (hIFN-γ) is amacrophage‐activating factor. IFN-γ is also implicated in resistance to NK cell and CTL responses and in immune escape in a variety of cancers. IFN-γ signaling does diverse biological functions primarily related to host defense and immune regulation, including antiviral and antibacterial defense, apoptosis, inflammation, and innate and acquired immunity.
Recombinant Human Interferon Gamma (IFN-γ) expressed the target gene encoding Gln24-Gln166.
Measured by a cytotoxicity assay using HT-29 cells, the ED50 for this effect is < 0.03 ng/ml.
Accession: P01579
Endotoxin < 0.01 EU/µg
Apparent Molecular Weight: 16~17 kDa, reducing conditions
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 5% Sucrose, 4% Mannitol, 0.02% Tween 80, pH7.4.
性状 | Lyophilized powder |
溶解性(25°C) | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
储存条件 | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
运输方式 | 冰袋运输,根据产品的不同,可能会有相应调整。 |
其他相关的Recombinant Proteins产品 |
---|
Recombinant Human Serpin A12 (E.coli, N-GST)
Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin is also a unique insulin sensitizing adipocytokine in obesity. |
Recombinant Human B2M Protein (Mammalian, C-6His)
β-2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family. B2M may adopt the fibrillar configuration of amyloid in certain pathologic states. |
Recombinant Mouse E-Selectin/CD62E Protein (HEK293)
E-selectin, also known as endothelial leukocyte adhesion molecule-1 (ELAM-1) and CD62E, is an inducible adhesion molecule that is expressed on the surfaces of stimulated vascular endothelial cells and is sometimes involved in cancer cell metastasis. |
Recombinant Human DPP4/CD26 (Mammalian, C-6His)
DPP4/CD26 is a signal-anchor for type II membrane protein that belongs to the peptidase S9B family. DPP4/CD26 acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. It’s binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. |
Recombinant Human USP14 (E.coli, N-6His)
USP14 belongs to the ubiquitin-specific processing (USP) family which is a deubiquitinating enzyme (DUB) with His and Cys domains. USP14 acts also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. |
产品仅供科学研究或药证申报的用途使用,不为任何个人或者非科研性质的其他用途提供服务。
Copyright © 2010-2022 AbMole版权所有 沪ICP备16047849号 沪公网安备 31011502012228号