Recombinant Human GC1q-R Protein (E. coli, C-6His) 别名：HABP1; C1qBP; ASF/SF2-Associated Protein p32; GC1QBP; 重组人GC1q-R 蛋白 (E. coli, C-6His)
GC1q-R Protein (C1QBP; HABP1) is a nucleus protein that belongs to the MAM33 family. C1QBP is known to bind to the globular heads of C1q molecules and inhibit C1 activation. Mitochondrial C1QBP is a critical mediator of p14ARF-induced apoptosis. C1QBP functions as a chemotactic factor for immature dendritic cells, and migration is mediated through ligation of both C1QBP and cC1qR/CR.
化学性质/溶解性/储存
| 性状 | Solution |
| 中文名称 | 重组人GC1q-R 蛋白 (E. coli, C-6His) |
| 储存条件 | Store at ≤-70°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
| 运输方式 | 冰袋运输，根据产品的不同，可能会有相应调整。 |
生物活性
GC1q-R Protein (C1QBP; HABP1) is a nucleus protein that belongs to the MAM33 family. C1QBP is known to bind to the globular heads of C1q molecules and inhibit C1 activation. Mitochondrial C1QBP is a critical mediator of p14ARF-induced apoptosis. C1QBP functions as a chemotactic factor for immature dendritic cells, and migration is mediated through ligation of both C1QBP and cC1qR/CR.
Recombinant Human GC1q-R Protein (C1QBP; HABP1) expressed the target gene encoding Leu74-Gln282 with a 6His tag at the C-terminus.
Accession: Q07021
Apparent Molecular Weight: 34 KDa, under reducing conditions
Endotoxin < 1 EU/µg
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 20% Glycerol, 1mM DTT, pH 7.5.
The product is shipped on dry ice packs. Upon receipt, store it immediately at the temperature listed below.
实验参考
建议您制定动物给药及实验方案时，尽量参考已发表的相关实验文献（溶剂种类及配比众多，简单地溶解目的化合物，并不能解决动物给药依从性、体内生物利用度、组织分布等相关问题，未必能保证目的化合物在动物体内充分发挥生物学效用）。
体内实验的工作液，建议您现用现配，当天使用；如在配制过程中出现沉淀、析出现象，可以通过超声和（或）加热的方式助溶。
切勿一次性将产品全部溶解。
请在下面的计算器中，输入您的动物实验相关数据并点击计算，即可得到该实验的总需药量和工作液终浓度。
例如您给药剂量是10 mg/kg，平均每只动物的体重为20 g，每只动物的给药体积是100 μL，动物数量为20只，则该动物实验的总需药量为4 mg，工作液终浓度为2 mg/mL。
1：鉴于实验过程的损耗，建议您至少多配1-2只动物的量；
2：为该产品最终给药时的浓度。
