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Recombinant Human CXCL10 (Mammalian, C-Fc-6His) 重组人CXCL10 (Mammalian, C-Fc-6His)

目录号 M25425 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types, such as monocytes, endothelial cells and fibroblasts, in response to IFN-γ. Recombinant Human CXCL10 is produced by Mammalian expression system and the target gene encoding Val22-Pro98 is expressed with a human IgG1 Fc, 6His tag at the C-terminus.

Recombinant Human CXCL10 (Mammalian, C-Fc-6His)结构式

别名:C-X-C Motif Chemokine 10; IP-10

规格 价格 库存状态
50ug ¥ 4320 中国库存现货
其他规格数量报价?

质量标准及产品资料
  • 纯度: >95%, Endotoxin < 1 EU/µg
  • COA
  • MSDS
生物活性

Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types, such as monocytes, endothelial cells and fibroblasts, in response to IFN-γ. CXCL10 has been attributed to several roles, such as chemoattraction for activated T-lymphocytes, inhibition of angiogenesis, and antitumor activity. Recombinant Human CXCL10 is produced by Mammalian expression system and the target gene encoding Val22-Pro98 is expressed with a human IgG1 Fc, 6His tag at the C-terminus.


Accession: P02778

APMol Mass: 35 KDa, reducing conditions

Endotoxin: < 1 EU/µg

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

化学性质
溶解性(25°C) Dissolve the lyophilized protein in distilled water. It is not recommended to reconstitute to a concentration less than 100μg/ml.
储存条件 Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
参考文献

[1] Xiaofei Li, et al. Oncoimmunology. CXCL10-armed oncolytic adenovirus promotes tumor-infiltrating T-cell chemotaxis to enhance anti-PD-1 therapy

[2] Zhiwen Shi, et al. Theranostics. CXCL10 potentiates immune checkpoint blockade therapy in homologous recombination-deficient tumors

[3] Xiaoyu Sun, et al. Cell Mol Immunol. Anti-inflammatory mechanisms of the novel cytokine interleukin-38 in allergic asthma

[4] Yuan Wei, et al. Gastroenterology. Plasma Cell Polarization to the Immunoglobulin G Phenotype in Hepatocellular Carcinomas Involves Epigenetic Alterations and Promotes Hepatoma Progression in Mice

[5] Annina M Hafner, et al. Adv Drug Deliv Rev. Particulate formulations for the delivery of poly(I:C) as vaccine adjuvant

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