重组激活素a（Activin A）是TGF-ß超家族的二聚糖蛋白，其作用包括胚胎分化、妊娠早期滋养层侵袭子宫壁等。激活素A还调节骨骼形成和再生，增强类风湿性关节炎的关节炎症，并触发呼吸系统的致病机制。
别名：Activin A; INHBA
重组激活素a（Activin A）是TGF-ß超家族的二聚糖蛋白，其作用包括胚胎分化、妊娠早期滋养层侵袭子宫壁等。激活素A还调节骨骼形成和再生，增强类风湿性关节炎的关节炎症，并触发呼吸系统的致病机制。激活素- a通过两种I型和两种Il型受体发出信号，在配体结合后，激活它们的激酶活性，磷酸化与SMAD4形成复合物的SMAD2和3细胞内信号介质，转运到细胞核，激活或沉默基因表达。
DNA序列编码人ActivinA（P08476）在HEK293细胞中表达。预测分子量为12.97kD。
Accession: P08476
Endotoxin < 0.1 EU/µg
Lyophilized from a 0.2 μm filtered solution of 4mM HCl.
| 性状 | Lyophilized powder |
| 储存条件 | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at ≤ -20°C for 3 months. |
| 运输方式 | 冰袋运输，根据产品的不同，可能会有相应调整。 |
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